-
- 抗原 See all ERN2 抗体
- ERN2 (Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2))
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This ERN2 antibody is un-conjugated
-
应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- Antigen affinity purification
- 免疫原
- Synthetic peptide of Human ERN2
- 亚型
- IgG
- Top Product
- Discover our top product ERN2 Primary Antibody
-
anti-Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2) antibody
ERN2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2) (AA 841-890) antibodyERN2 适用: 人, 小鼠 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- ELISA:1:2000-1:5000, IHC:1:50-1:200,
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- 抗原
- ERN2 (Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2))
- 别名
- ERN2 (ERN2 产品)
- 别名
- Ire1beta antibody, ire1b antibody, Ern1 antibody, Ire1 antibody, Ire1b antibody, IRE1-BETA antibody, IRE1b antibody, endoplasmic reticulum to nucleus signaling 2 antibody, endoplasmic reticulum (ER) to nucleus signalling 2 antibody, ERN2 antibody, ern2 antibody, Ern2 antibody
- 背景
-
Background: The accumulation of unfolded proteins within the endoplasmic recticulum (ER) of yeast and mammalian cells activates the unfolded protein response (UPR) pathway and leads to the transcription of ER-specific genes involved in protein folding. The activation of the UPR requires the ER transmembrane kinase IRE1p (for inositol-requiring and ER-to-nucleus signaling protein). IRE1α and IRE1β are two mammalian homologs of the yeast IRE1p. These related proteins localize to the ER lumen and contain both a short transmembrane domain that spans the ER membrane and a cytosolic Ser/Thr kinase domain. IRE1 activation involves the oligomerization and trans-phosphorylation of the cytosolic portion of the proteins, which then potentiates its intrinsic kinase activity and, in turn, stimulates transcription of UPR-targeted genes.
Aliases: ERN2 antibody, IRE2Serine/threonine-protein kinase/endoribonuclease IRE2 antibody, Endoplasmic reticulum-to-nucleus signaling 2 antibody, Inositol-requiring protein 2 antibody, hIRE2p antibody, Ire1-beta antibody, IRE1b) [Includes: Serine/threonine-protein kinase antibody, EC 2.7.11.1), Endoribonuclease antibody, EC 3.1.26.-)] antibody
- UniProt
- Q76MJ5
-
You are here:
