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RAD21 抗体

RAD21 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7184040
发货至: 中国
  • 抗原 See all RAD21 抗体
    RAD21 (RAD21 Homolog (RAD21))
    适用
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    宿主
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    克隆类型
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    多克隆
    标记
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    This RAD21 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), ELISA
    交叉反应
    人, 小鼠
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    免疫原
    Synthesized peptide derived from internal of Human RAD21.
    亚型
    IgG
    Top Product
    Discover our top product RAD21 Primary Antibody
  • 应用备注
    WB:1:500-1:3000,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    RAD21 (RAD21 Homolog (RAD21))
    别名
    RAD21 (RAD21 产品)
    别名
    rad21 antibody, wu:fb55d02 antibody, wu:fb93f04 antibody, CDLS4 antibody, HR21 antibody, HRAD21 antibody, MCD1 antibody, NXP1 antibody, SCC1 antibody, hHR21 antibody, mKIAA0078 antibody, hr21 antibody, mcd1 antibody, nxp-1 antibody, nxp1 antibody, scc1 antibody, xrad21 antibody, RAD21 cohesin complex component antibody, RAD21 cohesin complex component a antibody, RAD21 cohesin complex component L homeolog antibody, RAD21 cohesin complex component S homeolog antibody, R-spondin 2 antibody, RAD21 antibody, rad21a antibody, rad21.L antibody, Rad21 antibody, rad21.S antibody, RSPO2 antibody
    背景

    Background: Cleavable component of the cohesin complex, involved in chromosome cohesion during cell cycle, in DNA repair, and in apoptosis. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At metaphase-anaphase transition, this protein is cleaved by separase/ESPL1 and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Also plays a role in apoptosis, via its cleavage by caspase-3/CASP3 or caspase-7/CASP7 during early steps of apoptosis: the C-terminal 64 kDa cleavage product may act as a nuclear signal to initiate cytoplasmic events involved in the apoptotic pathway.

    McKay M.J., Genomics 36:305-315(1996).
    Sadano H., Biochem. Biophys. Res. Commun. 267:418-422(2000).
    Nomura N., DNA Res. 1:223-229(1994).

    Aliases: CDLS4 antibody, Double-strand-break repair protein rad21 homolog antibody, hHR21 antibody, HR21 antibody, HRAD21 antibody, KIAA0078 antibody, MCD1 antibody, Nuclear matrix protein 1 antibody, NXP-1 antibody, NXP1 antibody, Protein involved in DNA double-strand break repair antibody, RAD21 antibody, RAD21 homolog (S. pombe) antibody, RAD21 homolog antibody, RAD21_HUMAN antibody, Scc1 antibody, SCC1 homolog antibody

    UniProt
    O60216
    途径
    Positive Regulation of Endopeptidase Activity
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