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BRAF 抗体 (Ser446)

The 兔 多克隆 anti-BRAF antibody is suitable to detect BRAF in samples from 人. It has been validated for WB, ELISA 和 IHC.
产品编号 ABIN7179978
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for BRAF 抗体 (Ser446) (ABIN7179978)

抗原

See all BRAF 抗体
BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))

适用

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宿主

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克隆类型

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多克隆

标记

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This BRAF antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
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    Ser446

    原理

    BRAF (Ab-446) Antibody

    交叉反应

    小鼠

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized non-phosphopeptide derived from Human B-RAF around the phosphorylation site of serine 446 (R-D-S(p)-S-D).

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))

    别名

    BRAF

    背景

    Background: Protein kinase involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron. Phosphorylates MAP2K1, and thereby contributes to the MAP kinase signal transduction pathway.

    Stephens R.M., Mol. Cell. Biol. 12:3733-3742(1992).
    Albert S., Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
    Hillier L.W., Nature 424:157-164(2003)

    Aliases: FLJ95109 antibody, 94 kDa B raf protein antibody, B raf 1 antibody, B raf antibody, B Raf proto oncogene serine threonine protein kinase antibody, B Raf proto oncogene, serine/threonine kinase antibody, B RAF1 antibody, B-Raf proto-oncogene serine/threonine-protein kinase (p94) antibody, BRAF 1 antibody, BRAF antibody, BRAF_HUMAN antibody, BRAF1 antibody, cRmil antibody, MGC126806 antibody, MGC138284 antibody, Murine sarcoma viral (v-raf) oncogene homolog B1 antibody, Murine sarcoma viral v raf oncogene homolog B1 antibody, NS7 antibody, Oncogen BRAF antibody, oncogene BRAF1 antibody, p94 antibody, Proto-oncogene B-Raf antibody, Proto-oncogene c-Rmil antibody, RAFB 1 antibody, RAFB1 antibody, RMIL antibody, Serine/threonine-protein kinase B-raf antibody, v raf murine sarcoma viral oncogene homolog B antibody, v raf murine sarcoma viral oncogene homolog B1 antibody, v-Raf murine sarcoma viral oncogene homolog B1 antibody

    UniProt

    P15056

    途径

    MAPK Pathway, RTK signaling, Neurotrophin Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Hepatitis C, Autophagy
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