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p53 抗体 (AA 1-391)

This anti-p53 antibody is a 兔 多克隆 antibody detecting p53 in WB 和 ELISA. Suitable for 大鼠.
产品编号 ABIN7178833
发货至: 中国

Quick Overview for p53 抗体 (AA 1-391) (ABIN7178833)

抗原

See all p53 (TP53) 抗体
p53 (TP53) (Tumor Protein P53 (TP53))

适用

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大鼠

宿主

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克隆类型

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多克隆

标记

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This p53 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 1-391

    交叉反应

    小鼠, 大鼠

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Rat Cellular tumor antigen p53 protein (1-391AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: WB:1:500-1:5000,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    p53 (TP53) (Tumor Protein P53 (TP53))

    别名

    Tp53

    背景

    Background: Acts as a tumor suppressor in many tumor types, induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression By similarity. Interacts with GRK5

    Aliases: Tp53 antibody, P53 antibody, Cellular tumor antigen p53 antibody, Tumor suppressor p53 antibody

    UniProt

    P10361

    途径

    p53 Pathway, MAPK Pathway, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect
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