DPF1 抗体 (AA 261-380)
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- 抗原 See all DPF1 抗体
- DPF1 (D4, Zinc and Double PHD Fingers Family 1 (DPF1))
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抗原表位
- AA 261-380
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DPF1 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human Zinc finger protein neuro-d4 protein (261-380AA)
- 亚型
- IgG
- Top Product
- Discover our top product DPF1 Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- DPF1 (D4, Zinc and Double PHD Fingers Family 1 (DPF1))
- 别名
- DPF1 (DPF1 产品)
- 别名
- zgc:110104 antibody, DPF1 antibody, req antibody, xReq antibody, neud4 antibody, requiem antibody, neuro-d4 antibody, BAF45b antibody, NEUD4 antibody, Neud4 antibody, D4, zinc and double PHD fingers family 1 antibody, double PHD fingers 1 antibody, dpf1 antibody, DPF1 antibody, Dpf1 antibody
- 背景
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Background: May have an important role in developing neurons by participating in regulation of cell survival, possibly as a neurospecific transcription factor. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity).
Aliases: BAF45B antibody, BRG1-associated factor 45B antibody, D4 antibody, D4 zinc and double PHD fingers family 1 antibody, DPF1 antibody, DPF1_HUMAN antibody, NEUD4 antibody, Neuro d4 homolog antibody, Zinc and double PHD fingers family 1 antibody, Zinc finger protein neuro-d4 antibody
- UniProt
- Q92782
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