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DPF1 抗体

DPF1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7468200
发货至: 中国
  • 抗原 See all DPF1 抗体
    DPF1 (D4, Zinc and Double PHD Fingers Family 1 (DPF1))
    适用
    • 20
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 20
    • 1
    克隆类型
    • 21
    多克隆
    标记
    • 11
    • 2
    • 2
    • 2
    • 2
    • 2
    This DPF1 antibody is un-conjugated
    应用范围
    • 18
    • 17
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    交叉反应
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human DPF1. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product DPF1 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: IMR32 , U87-MG

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.85 mg/mL
    缓冲液
    0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    DPF1 (D4, Zinc and Double PHD Fingers Family 1 (DPF1))
    别名
    double PHD fingers 1 (DPF1 产品)
    别名
    zgc:110104 antibody, DPF1 antibody, req antibody, xReq antibody, neud4 antibody, requiem antibody, neuro-d4 antibody, BAF45b antibody, NEUD4 antibody, Neud4 antibody, D4, zinc and double PHD fingers family 1 antibody, double PHD fingers 1 antibody, dpf1 antibody, DPF1 antibody, Dpf1 antibody
    背景

    Synonyms: double PHD fingers 1 , BAF45b , NEUD4 , neuro-d4

    Background: May have an important role in developing neurons by participating in regulation of cell survival, possibly as a neurospecific transcription factor. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth.

    分子量
    43 kDa
    基因ID
    8193
    UniProt
    Q92782
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