电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

VPS16 抗体 (AA 7-89) (FITC)

VPS16 适用: 人 宿主: 兔 Polyclonal FITC
产品编号 ABIN7175668
发货至: 中国
  • 抗原 See all VPS16 抗体
    VPS16 (Vacuolar Protein Sorting-Associated Protein 16 Homolog (VPS16))
    抗原表位
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 7-89
    适用
    • 29
    • 9
    • 9
    • 5
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    宿主
    • 23
    • 4
    • 2
    克隆类型
    • 27
    • 2
    多克隆
    标记
    • 20
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This VPS16 antibody is conjugated to FITC
    应用范围
    请咨询
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human VPS16 protein (7-89AA)
    亚型
    IgG
    Top Product
    Discover our top product VPS16 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    VPS16 (Vacuolar Protein Sorting-Associated Protein 16 Homolog (VPS16))
    别名
    VPS16 (VPS16 产品)
    别名
    1810074M16Rik antibody, hVPS16 antibody, VPS16A antibody, vacuolar protein sorting protein 16 antibody, Vacuolar protein sorting-associated protein 16 homolog antibody, VSP16 CORVET/HOPS core subunit antibody, VPS16, CORVET/HOPS core subunit antibody, vacuolar protein sorting 16 homolog (S. cerevisiae) antibody, VPS16 CORVET/HOPS core subunit antibody, Tc00.1047053506367.60 antibody, Tc00.1047053508355.200 antibody, vps-16 antibody, Vps16 antibody, VPS16 antibody
    背景

    Background: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to Rab7 on the late endosomal membrane and to regulate late endocytic, phagocytic and autophagic traffic towards lysosomes. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations (PubMed:11382755, PubMed:23351085, PubMed:24554770, PubMed:25266290, PubMed:25783203). Required for recruitment of VPS33A to the HOPS complex (PubMed:23901104). Required for fusion of endosomes and autophagosomes with lysosomes, the function is dependent on its association with VPS33A but not VPS33B (PubMed:25783203). The function in autophagosome-lysosome fusion implicates STX17 but not UVRAG (PubMed:24554770).

    Aliases: Vacuolar protein sorting-associated protein 16 homolog (hVPS16), VPS16

    UniProt
    Q6GMQ7
You are here: