VPS16 抗体 (Internal Region)
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- 抗原 See all VPS16 抗体
- VPS16 (Vacuolar Protein Sorting-Associated Protein 16 Homolog (VPS16))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This VPS16 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- VPS16 Antibody detects endogenous levels of total VPS16.
- 预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human VPS16, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product VPS16 Primary Antibody
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anti-Vacuolar Protein Sorting-Associated Protein 16 Homolog (VPS16) (AA 7-89) antibody
VPS16 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 16 Homolog (VPS16) (AA 754-839) antibodyVPS16 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2F10 unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 16 Homolog (VPS16) (Internal Region) antibodyVerified VPS16 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 16 Homolog (VPS16) (C-Term) antibodyVPS16 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 16 Homolog (VPS16) antibodyVPS16 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 16 Homolog (VPS16) (AA 587-636) antibodyVPS16 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 犬, Pig, Bat, 猴, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 16 Homolog (VPS16) (C-Term) antibodyVPS16 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 犬, Pig, Bat, 猴, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 16 Homolog (VPS16) (AA 1-839) antibodyVPS16 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 16 Homolog (VPS16) (Internal Region) antibodyVerified VPS16 适用: 人, 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 16 Homolog (VPS16) (AA 540-839) antibodyVPS16 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- VPS16 (Vacuolar Protein Sorting-Associated Protein 16 Homolog (VPS16))
- 别名
- VPS16 (VPS16 产品)
- 别名
- 1810074M16Rik antibody, hVPS16 antibody, VPS16A antibody, vacuolar protein sorting protein 16 antibody, Vacuolar protein sorting-associated protein 16 homolog antibody, VSP16 CORVET/HOPS core subunit antibody, VPS16, CORVET/HOPS core subunit antibody, vacuolar protein sorting 16 homolog (S. cerevisiae) antibody, VPS16 CORVET/HOPS core subunit antibody, Tc00.1047053506367.60 antibody, Tc00.1047053508355.200 antibody, vps-16 antibody, Vps16 antibody, VPS16 antibody
- 背景
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Description: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to Rab7 on the late endosomal membrane and to regulate late endocytic, phagocytic and autophagic traffic towards lysosomes. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations (PubMed:11382755, PubMed:23351085, PubMed:24554770, PubMed:25266290, PubMed:25783203). Required for recruitment of VPS33A to the HOPS complex (PubMed:23901104). Required for fusion of endosomes and autophagosomes with lysosomes, the function is dependent on its association with VPS33A but not VPS33B (PubMed:25783203). The function in autophagosome-lysosome fusion implicates STX17 but not UVRAG (PubMed:24554770).
Gene: VPS16
- 分子量
- 95 kDa
- 基因ID
- 64601
- UniProt
- Q9H269
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