KCNAB1 抗体 (AA 287-401)
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- 抗原 See all KCNAB1 抗体
- KCNAB1 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, beta Member 1 (KCNAB1))
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抗原表位
- AA 287-401
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KCNAB1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人, 小鼠
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Voltage-gated potassium channel subunit beta-1 protein (287-401AA)
- 亚型
- IgG
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anti-Potassium Voltage-Gated Channel, Shaker-Related Subfamily, beta Member 1 (KCNAB1) antibody
KCNAB1 适用: 人 WB, IF, FACS 宿主: 小鼠 Monoclonal 2F1 unconjugated
anti-Potassium Voltage-Gated Channel, Shaker-Related Subfamily, beta Member 1 (KCNAB1) (C-Term) antibodyKCNAB1 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Potassium Voltage-Gated Channel, Shaker-Related Subfamily, beta Member 1 (KCNAB1) (C-Term) antibodyKCNAB1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Potassium Voltage-Gated Channel, Shaker-Related Subfamily, beta Member 1 (KCNAB1) (AA 311-360) antibodyKCNAB1 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Potassium Voltage-Gated Channel, Shaker-Related Subfamily, beta Member 1 (KCNAB1) (AA 282-401) antibodyKCNAB1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Potassium Voltage-Gated Channel, Shaker-Related Subfamily, beta Member 1 (KCNAB1) (AA 15-44), (N-Term) antibodyKCNAB1 适用: 人 WB 宿主: 兔 Polyclonal RB40526 unconjugated
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- 应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- KCNAB1 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, beta Member 1 (KCNAB1))
- 别名
- KCNAB1 (KCNAB1 产品)
- 别名
- KCNAB1 antibody, zgc:113627 antibody, AKR6A3 antibody, KCNA1B antibody, KV-BETA-1 antibody, Kvb1.3 antibody, hKvBeta3 antibody, hKvb3 antibody, Kvbeta1.1 antibody, KVBETA1 antibody, Kv-beta-1 antibody, Akr8a8 antibody, mKv(beta)1 antibody, KvBeta3 antibody, potassium voltage-gated channel subfamily A member regulatory beta subunit 1 antibody, potassium voltage-gated channel, shaker-related subfamily, beta member 1 a antibody, potassium voltage-gated channel, shaker-related subfamily, beta member 1 antibody, KCNAB1 antibody, kcnab1a antibody, Kcnab1 antibody
- 背景
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Background: Cytoplasmic potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits (PubMed:7499366, PubMed:7603988, PubMed:17156368,PubMed:17540341, PubMed:19713757). Modulates action potentials via its effect on the pore-forming alpha subunits (By similarity). Promotes expression of the pore-forming alpha subunits at the cell membrane, and thereby increases channel activity (By similarity). Mediates closure of delayed rectifier potassium channels by physically obstructing the pore via its N-terminal domain and increases the speed of channel closure for other family members (PubMed:9763623). Promotes the closure of KCNA1, KCNA2 and KCNA5 channels (PubMed:7499366, PubMed:7890032, PubMed:7603988, PubMed:7649300, PubMed:8938711, PubMed:12077175, PubMed:12130714, PubMed:15361858, PubMed:17540341, PubMed:19713757). Accelerates KCNA4 channel closure (PubMed:7890032, PubMed:7649300, PubMed:7890764, PubMed:9763623). Accelerates the closure of heteromeric channels formed by KCNA1 and KCNA4 (PubMed:17156368). Accelerates the closure of heteromeric channels formed by KCNA2, KCNA5 and KCNA6 (By similarity). Isoform KvB1.2 has no effect on KCNA1, KCNA2 or KCNB1 (PubMed:7890032, PubMed:7890764). Enhances KCNB1 and KCNB2 channel activity (By similarity). Binds NADPH, this is required for efficient down-regulation of potassium channel activity (PubMed:17540341). Has NADPH-dependent aldoketoreductase activity (By similarity). Oxidation of the bound NADPH strongly decreases N-type inactivation of potassium channel activity (By similarity).
Aliases: hKvb3 antibody, hKvBeta3 antibody, K(+) channel subunit beta-1 antibody, KCAB1_HUMAN antibody, KCNA1B antibody, KCNAB1 antibody, Kv-beta-1 antibody, Kvb1.3 antibody, Voltage-gated potassium channel beta-1 subunit antibody, Voltage-gated potassium channel subunit beta-1 antibody
- UniProt
- Q14722
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