KCNAB1 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for KCNAB1 抗体 (N-Term) (ABIN1881473)
抗原
See all KCNAB1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 15-44, N-Term
-
纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
-
免疫原
- This KCNAB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-44 amino acids from the N-terminal region of human KCNAB1.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- WB: 1:1000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
有效期
- 6 months
-
-
-
: "Structural determinants of Kvbeta1.3-induced channel inactivation: a hairpin modulated by PIP2." in: The EMBO journal, Vol. 27, Issue 23, pp. 3164-74, (2008) (PubMed).
: "Multicentre search for genetic susceptibility loci in sporadic epilepsy syndrome and seizure types: a case-control study...." in: Lancet neurology, Vol. 6, Issue 11, pp. 970-80, (2007) (PubMed).
: "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." in: Genomics, Vol. 89, Issue 3, pp. 307-15, (2007) (PubMed).
: "Role of macrophage oxidative burst in the action of anthrax lethal toxin." in: Molecular medicine (Cambridge, Mass.), Vol. 1, Issue 1, pp. 7-18, (1996) (PubMed).
-
: "Structural determinants of Kvbeta1.3-induced channel inactivation: a hairpin modulated by PIP2." in: The EMBO journal, Vol. 27, Issue 23, pp. 3164-74, (2008) (PubMed).
-
- KCNAB1 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, beta Member 1 (KCNAB1))
-
别名
- KCNAB1
-
背景
- Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member includes three distinct isoforms which are encoded by three alternatively spliced transcript variants of this gene. These three isoforms are beta subunits, which form heteromultimeric complex with alpha subunits and modulate the activity of the pore-forming alpha subunits.
-
分子量
- 46563
-
NCBI登录号
- NP_003462, NP_751891, NP_751892
-
UniProt
- Q14722
抗原
-