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KCNAB1 抗体 (N-Term)

KCNAB1 适用: 人 WB 宿主: 兔 Polyclonal RB40526 unconjugated
产品编号 ABIN1881473
发货至: 中国
  • 抗原 See all KCNAB1 抗体
    KCNAB1 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, beta Member 1 (KCNAB1))
    抗原表位
    • 15
    • 7
    • 7
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    AA 15-44, N-Term
    适用
    • 41
    • 20
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 40
    • 2
    克隆类型
    • 40
    • 2
    多克隆
    标记
    • 14
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KCNAB1 antibody is un-conjugated
    应用范围
    • 37
    • 22
    • 13
    • 13
    • 6
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This KCNAB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-44 amino acids from the N-terminal region of human KCNAB1.
    克隆位点
    RB40526
    亚型
    Ig Fraction
    Top Product
    Discover our top product KCNAB1 Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Decher, Gonzalez, Streit, Sachse, Renigunta, Soom, Heinemann, Daut, Sanguinetti: "Structural determinants of Kvbeta1.3-induced channel inactivation: a hairpin modulated by PIP2." in: The EMBO journal, Vol. 27, Issue 23, pp. 3164-74, (2008) (PubMed).

    Cavalleri, Weale, Shianna, Singh, Lynch, Grinton, Szoeke, Murphy, Kinirons, ORourke, Ge, Depondt, Claeys, Pandolfo, Gumbs, Walley, McNamara, Mulley, Linney, Sheffield, Radtke, Tate, Chissoe et al.: "Multicentre search for genetic susceptibility loci in sporadic epilepsy syndrome and seizure types: a case-control study...." in: Lancet neurology, Vol. 6, Issue 11, pp. 970-80, (2007) (PubMed).

    Lamesch, Li, Milstein, Fan, Hao, Szabo, Hu, Venkatesan, Bethel, Martin, Rogers, Lawlor, McLaren, Dricot, Borick, Cusick, Vandenhaute, Dunham, Hill, Vidal: "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." in: Genomics, Vol. 89, Issue 3, pp. 307-15, (2007) (PubMed).

    Hanna, Kruskal, Ezekowitz, Bloom, Collier: "Role of macrophage oxidative burst in the action of anthrax lethal toxin." in: Molecular medicine (Cambridge, Mass.), Vol. 1, Issue 1, pp. 7-18, (1996) (PubMed).

  • 抗原
    KCNAB1 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, beta Member 1 (KCNAB1))
    别名
    KCNAB1 (KCNAB1 产品)
    别名
    KCNAB1 antibody, zgc:113627 antibody, AKR6A3 antibody, KCNA1B antibody, KV-BETA-1 antibody, Kvb1.3 antibody, hKvBeta3 antibody, hKvb3 antibody, Kvbeta1.1 antibody, KVBETA1 antibody, Kv-beta-1 antibody, Akr8a8 antibody, mKv(beta)1 antibody, KvBeta3 antibody, potassium voltage-gated channel subfamily A member regulatory beta subunit 1 antibody, potassium voltage-gated channel, shaker-related subfamily, beta member 1 a antibody, potassium voltage-gated channel, shaker-related subfamily, beta member 1 antibody, KCNAB1 antibody, kcnab1a antibody, Kcnab1 antibody
    背景
    Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member includes three distinct isoforms which are encoded by three alternatively spliced transcript variants of this gene. These three isoforms are beta subunits, which form heteromultimeric complex with alpha subunits and modulate the activity of the pore-forming alpha subunits.
    分子量
    46563
    NCBI登录号
    NP_003462, NP_751891, NP_751892
    UniProt
    Q14722
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