VPS26B 抗体 (AA 1-336)
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- 抗原 See all VPS26B 抗体
- VPS26B (Vacuolar Protein Sorting 26 Homolog B (VPS26B))
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抗原表位
- AA 1-336
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This VPS26B antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Vacuolar protein sorting-associated protein 26B protein (1-336AA)
- 亚型
- IgG
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- 应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- VPS26B (Vacuolar Protein Sorting 26 Homolog B (VPS26B))
- 别名
- VPS26B (VPS26B 产品)
- 别名
- VPS26B antibody, wu:fb49d07 antibody, wu:fb50d06 antibody, zgc:56297 antibody, pep8b antibody, vps26b antibody, Pep8b antibody, VP26B antibody, 1810012I05Rik antibody, 2310075A12Rik antibody, AI848392 antibody, T29A15.180 antibody, T29A15_180 antibody, vacuolar protein sorting 26B antibody, vacuolar protein sorting 26 homolog B (S. pombe) antibody, VPS26, retromer complex component B antibody, VPS26 retromer complex component B antibody, VPS26 retromer complex component B S homeolog antibody, vacuolar protein sorting 26B antibody, VPS26B antibody, vps26b antibody, vps26b.S antibody, Vps26b antibody
- 背景
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Background: Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX3-retromer mediates the retrograde transport of WLS distinct from the SNX-BAR retromer pathway. The SNX27-retromer is believed to be involved in endosome-to-plasma membrane trafficking and recycling of a broad spectrum of cargo proteins. The CSC seems to act as recruitment hub for other proteins, such as the WASH complex and TBC1D5. May be involved in retrograde transport of SORT1 but not of IGF2R. Acts redundantly with VSP26A in SNX-27 mediated endocytic recycling of SLC2A1/GLUT1 (By similarity).
Aliases: Pep8b antibody, Vacuolar protein sorting 26 homolog B (S. pombe) antibody, Vacuolar protein sorting 26 homolog B (yeast) antibody, Vacuolar protein sorting-associated protein 26B antibody, Vesicle protein sorting 26B antibody, VP26B_HUMAN antibody, VPS26B antibody
- UniProt
- Q4G0F5
- 途径
- Cellular Glucan Metabolic Process
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