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VPS26B 抗体 (Internal Region)

VPS26B 适用: 人, 小鼠 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6258353
发货至: 中国
  • 抗原 See all VPS26B 抗体
    VPS26B (Vacuolar Protein Sorting 26 Homolog B (VPS26B))
    抗原表位
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 16
    • 14
    • 10
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 16
    克隆类型
    • 16
    多克隆
    标记
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This VPS26B antibody is un-conjugated
    应用范围
    • 8
    • 7
    • 2
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    VPS26B Antibody detects endogenous levels of total VPS26B.
    预测反应
    Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human VPS26B, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product VPS26B Primary Antibody
  • 应用备注
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    VPS26B (Vacuolar Protein Sorting 26 Homolog B (VPS26B))
    别名
    VPS26B (VPS26B 产品)
    别名
    VPS26B antibody, wu:fb49d07 antibody, wu:fb50d06 antibody, zgc:56297 antibody, pep8b antibody, vps26b antibody, Pep8b antibody, VP26B antibody, 1810012I05Rik antibody, 2310075A12Rik antibody, AI848392 antibody, T29A15.180 antibody, T29A15_180 antibody, vacuolar protein sorting 26B antibody, vacuolar protein sorting 26 homolog B (S. pombe) antibody, VPS26, retromer complex component B antibody, VPS26 retromer complex component B antibody, VPS26 retromer complex component B S homeolog antibody, vacuolar protein sorting 26B antibody, VPS26B antibody, vps26b antibody, vps26b.S antibody, Vps26b antibody
    背景

    Description: Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX3-retromer mediates the retrograde transport of WLS distinct from the SNX-BAR retromer pathway. The SNX27-retromer is believed to be involved in endosome-to-plasma membrane trafficking and recycling of a broad spectrum of cargo proteins. The CSC seems to act as recruitment hub for other proteins, such as the WASH complex and TBC1D5. May be involved in retrograde transport of SORT1 but not of IGF2R. Acts redundantly with VSP26A in SNX-27 mediated endocytic recycling of SLC2A1/GLUT1 (By similarity).

    Gene: VPS26B

    分子量
    45 kDa
    基因ID
    112936
    UniProt
    Q4G0F5
    途径
    Cellular Glucan Metabolic Process
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