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UBA52 抗体 (AA 1-128) (Biotin)

UBA52 适用: 人 ELISA 宿主: 兔 Polyclonal Biotin
产品编号 ABIN7174410
发货至: 中国
  • 抗原 See all UBA52 抗体
    UBA52 (Ubiquitin A-52 Residue Ribosomal Protein Fusion Product 1 (UBA52))
    抗原表位
    • 12
    • 7
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-128
    适用
    • 45
    • 11
    • 11
    宿主
    • 41
    • 4
    克隆类型
    • 41
    • 4
    多克隆
    标记
    • 19
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This UBA52 antibody is conjugated to Biotin
    应用范围
    • 24
    • 22
    • 22
    • 13
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    ELISA
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Ubiquitin-60S ribosomal protein L40 protein (1-128AA)
    亚型
    IgG
    Top Product
    Discover our top product UBA52 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    UBA52 (Ubiquitin A-52 Residue Ribosomal Protein Fusion Product 1 (UBA52))
    别名
    UBA52 (UBA52 产品)
    别名
    CEP52 antibody, HUBCEP52 antibody, L40 antibody, RPL40 antibody, D8Ertd21e antibody, Gm1863 antibody, Rps27a antibody, Ubb antibody, Ubc antibody, UBCEP2 antibody, UB-RPL40 antibody, MGC80109 antibody, cep52 antibody, hubcep52 antibody, rpl40 antibody, RPS27A antibody, UBB antibody, UBC antibody, wu:fa91f08 antibody, zgc:123344 antibody, UBA52 antibody, ubiquitin A-52 residue ribosomal protein fusion product 1 antibody, ubiquitin A-52 residue ribosomal protein fusion product 1 L homeolog antibody, UBA52 antibody, Uba52 antibody, uba52.L antibody, uba52 antibody
    背景

    Background: Ubiquitin: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair, Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation, Lys-29-linked is involved in lysosomal degradation, Lys-33-linked is involved in kinase modification, Lys-48-linked is involved in protein degradation via the proteasome, Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling.

    Aliases: UBA52 antibody, UBCEP2 antibody, Ubiquitin-60S ribosomal protein L40 antibody, CEP52 antibody, Ubiquitin A-52 residue ribosomal protein fusion product 1) [Cleaved into: Ubiquitin, 60S ribosomal protein L40 antibody, Large ribosomal subunit protein eL40)] antibody

    UniProt
    P62987
    途径
    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, Toll-Like Receptors Cascades, Synthesis of DNA, EGFR Downregulation
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