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UBA52 抗体 (Internal Region)

UBA52 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6265860
发货至: 中国
  • 抗原 See all UBA52 抗体
    UBA52 (Ubiquitin A-52 Residue Ribosomal Protein Fusion Product 1 (UBA52))
    抗原表位
    • 12
    • 7
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    Internal Region
    适用
    人, 小鼠, 大鼠
    宿主
    • 41
    • 4
    克隆类型
    • 41
    • 4
    多克隆
    标记
    • 18
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This UBA52 antibody is un-conjugated
    应用范围
    • 23
    • 22
    • 21
    • 13
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    特异性
    UBA52 Antibody detects endogenous levels of total UBA52.
    预测反应
    Pig,Zebrafish,Bovine,Horse,Sheep,Dog,Chicken,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human UBA52, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product UBA52 Primary Antibody
  • 应用备注
    IHC 1:50-1:200, WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    UBA52 (Ubiquitin A-52 Residue Ribosomal Protein Fusion Product 1 (UBA52))
    别名
    UBA52 (UBA52 产品)
    别名
    CEP52 antibody, HUBCEP52 antibody, L40 antibody, RPL40 antibody, D8Ertd21e antibody, Gm1863 antibody, Rps27a antibody, Ubb antibody, Ubc antibody, UBCEP2 antibody, UB-RPL40 antibody, MGC80109 antibody, cep52 antibody, hubcep52 antibody, rpl40 antibody, RPS27A antibody, UBB antibody, UBC antibody, wu:fa91f08 antibody, zgc:123344 antibody, UBA52 antibody, ubiquitin A-52 residue ribosomal protein fusion product 1 antibody, ubiquitin A-52 residue ribosomal protein fusion product 1 L homeolog antibody, UBA52 antibody, Uba52 antibody, uba52.L antibody, uba52 antibody
    背景

    Description: Ubiquitin: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair, Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation, Lys-29-linked is involved in lysosomal degradation, Lys-33-linked is involved in kinase modification, Lys-48-linked is involved in protein degradation via the proteasome, Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling.

    Gene: UBA52

    分子量
    8kDa
    基因ID
    7311
    UniProt
    P62987
    途径
    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, Toll-Like Receptors Cascades, Synthesis of DNA, EGFR Downregulation
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