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- 抗原 See all RANKL (TNFSF11) 抗体
- RANKL (TNFSF11) (Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))
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抗原表位
- AA 73-306
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RANKL antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Tumor necrosis factor ligand superfamily member 11 protein (73-306AA)
- 亚型
- IgG
- Top Product
- Discover our top product TNFSF11 Primary Antibody
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anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) (AA 221-300) antibody
TNFSF11 适用: 人, 小鼠, 大鼠, 兔 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) (AA 74-308) antibodyTNFSF11 适用: 人, 猴 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 8A7B9 unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) (AA 10-90) antibodyTNFSF11 适用: 人, 小鼠 WB, ELISA, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) (AA 74-308) antibodyTNFSF11 适用: 人 WB, ELISA, IHC, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 3H8A7 unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) (AA 210-317) antibodyTNFSF11 适用: 人, 小鼠, 大鼠, 兔 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) (C-Term) antibodyTNFSF11 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) (AA 78-317) antibodyTNFSF11 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) (AA 74-308) antibodyTNFSF11 适用: 人, 猴 WB, ELISA, IHC, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 7G3D7 unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) (AA 92-263) antibodyTNFSF11 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) (AA 106-240) antibodyTNFSF11 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- RANKL (TNFSF11) (Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))
- 别名
- TNFSF11 (TNFSF11 产品)
- 别名
- CD254 antibody, ODF antibody, OPGL antibody, OPTB2 antibody, RANKL antibody, TRANCE antibody, hRANKL2 antibody, sOdf antibody, TNFSF11 antibody, Ly109l antibody, OPG antibody, Trance antibody, cd254 antibody, odf antibody, opgl antibody, optb2 antibody, rankl antibody, sodf antibody, tnfsf11 antibody, trance antibody, TNF superfamily member 11 antibody, tumor necrosis factor (ligand) superfamily, member 11 antibody, TNF receptor superfamily member 11b antibody, TNF superfamily member 11 L homeolog antibody, TNFSF11 antibody, Tnfsf11 antibody, TNFRSF11B antibody, tnfsf11.L antibody
- 背景
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Background: Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy (PubMed:22664871). Induces osteoclastogenesis by activating multiple signaling pathways in osteoclast precursor cells, chief among which is induction of long lasting oscillations in the intracellular concentration of Ca (2+) resulting in the activation of NFATC1, which translocates to the nucleus and induces osteoclast-specific gene transcription to allow differentiation of osteoclasts. During osteoclast differentiation, in a TMEM64 and ATP2A2-dependent manner induces activation of CREB1 and mitochondrial ROS generation necessary for proper osteoclast generation (By similarity).
Aliases: CD254 antibody, hRANKL2 antibody, ODF antibody, OPGL antibody, OPTB2 antibody, Osteoclast differentiation factor antibody, Osteoprotegerin ligand antibody, RANKL antibody, Receptor activator of NF-kappa-B ligand antibody, Receptor activator of nuclear factor kappa B ligand antibody, Receptor activator of nuclear factor kappa-B ligand antibody, sOdf antibody, soluble form antibody, TNF-related activation-induced cytokine antibody, TNF11_HUMAN antibody, Tnfsf11 antibody, TRANCE antibody, Tumor necrosis factor (ligand) superfamily member 11 antibody, Tumor necrosis factor ligand superfamily member 11 antibody
- UniProt
- O14788
- 途径
- NF-kappaB Signaling
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