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- 抗原 See all STAT1 抗体
- STAT1 (Signal Transducer and Activator of Transcription 1, 91kDa (STAT1))
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抗原表位
- AA 63-196
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This STAT1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Signal transducer and activator of transcription 1-alpha/beta protein (63-196AA)
- 亚型
- IgG
- Top Product
- Discover our top product STAT1 Primary Antibody
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anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (pSer727) antibody
STAT1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 343-602) antibodySTAT1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (pSer727) antibodySTAT1 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) antibodySTAT1 适用: 人, 犬, 猴 WB, IHC, IHC (p), IF 宿主: 小鼠 Monoclonal 4H9 unconjugated
anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 717-745), (C-Term) antibodySTAT1 适用: 人 WB, IHC (p), IF, FACS 宿主: 兔 Polyclonal RB41406 unconjugated
anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 1-712) antibodySTAT1 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 650-750) antibodySTAT1 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 513-712) antibodySTAT1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 1-712) antibodySTAT1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 613-712) antibodySTAT1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1A8 unconjugated
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- 应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- STAT1 (Signal Transducer and Activator of Transcription 1, 91kDa (STAT1))
- 别名
- STAT1 (STAT1 产品)
- 别名
- CANDF7 antibody, ISGF-3 antibody, STAT91 antibody, 2010005J02Rik antibody, AA408197 antibody, XStat1 antibody, STAT4 antibody, DD6G4-4 antibody, STAT antibody, STAT1 antibody, dZ182H3.3 antibody, si:by134g18.2 antibody, si:by51f19.1 antibody, si:dz182h3.3 antibody, si:dz199m19.1 antibody, si:dz73o4.2 antibody, stat1 antibody, signal transducer and activator of transcription 1 antibody, signal transducer and activator of transcription 1 L homeolog antibody, signal transducer and activator of transcription 1, 91kDa antibody, signal transducer and activator of transcription 4 antibody, signal transducer and activator of transcription 1a antibody, STAT1 antibody, Stat1 antibody, stat1.L antibody, stat4 antibody, stat1a antibody
- 背景
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Background: Signal transducer and transcription activator that mediates cellular responses to interferons (IFNs), cytokine KITLG/SCF and other cytokines and other growth factors. Following type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors, signaling via protein kinases leads to activation of Jak kinases (TYK2 and JAK1) and to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize and associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of IFN-stimulated genes (ISG), which drive the cell in an antiviral state. In response to type II IFN (IFN-gamma), STAT1 is tyrosine- and serine-phosphorylated. It then forms a homodimer termed IFN-gamma-activated factor (GAF), migrates into the nucleus and binds to the IFN gamma activated sequence (GAS) to drive the expression of the target genes, inducing a cellular antiviral state. Becomes activated in response to KITLG/SCF and KIT signaling. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4.
Aliases: Signal transducer and activator of transcription 1 91kD antibody, CANDF7 antibody, DKFZp686B04100 antibody, IMD31A antibody, IMD31B antibody, IMD31C antibody, ISGF 3 antibody, ISGF-3 antibody, OTTHUMP00000163552 antibody, OTTHUMP00000165046 antibody, OTTHUMP00000165047 antibody, OTTHUMP00000205845 antibody, Signal transducer and activator of transcription 1 91 kDa antibody, Signal transducer and activator of transcription 1 antibody, Signal transducer and activator of transcription 1, 91kD antibody, Signal transducer and activator of transcription 1-alpha/beta antibody, STAT 1 antibody, Stat1 antibody, STAT1_HUMAN antibody, STAT91 antibody, Transcription factor ISGF 3 components p91 p84 antibody, Transcription factor ISGF-3 components p91/p84 antibody, Transcription factor ISGF3 components p91/p84 antibody, XStat1 antibody
- UniProt
- P42224
- 途径
- JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Hepatitis C, CXCR4-mediated Signaling Events
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