ATP8A1 抗体 (AA 448-545)
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- 抗原 See all ATP8A1 抗体
- ATP8A1 (ATPase, Class I, Type 8A, Member 1 (ATP8A1))
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抗原表位
- AA 448-545
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ATP8A1 antibody is un-conjugated
- 应用范围
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Phospholipid-transporting ATPase IA protein (448-545AA)
- 亚型
- IgG
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- 应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- ATP8A1 (ATPase, Class I, Type 8A, Member 1 (ATP8A1))
- 别名
- ATP8A1 (ATP8A1 产品)
- 别名
- ATPASEII antibody, ATPIA antibody, ATPP2 antibody, AI481521 antibody, AI853962 antibody, APLT antibody, AW743152 antibody, AW822227 antibody, Atp3a2 antibody, B230107D19Rik antibody, ClassI antibody, mKIAA4233 antibody, ATPase phospholipid transporting 8A1 antibody, ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 antibody, Atp8a1 antibody, ATP8A1 antibody
- 背景
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Background: Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. In vitro, its ATPase activity is selectively and stereospecifically stimulated by phosphatidylserine (PS). The flippase complex ATP8A1:TMEM30A seems to play a role in regulation of cell migration probably involving flippase-mediated translocation of phosphatidylethanolamine (PE) at the plasma membrane. Acts as aminophospholipid translocase at the plasma membrane in neuronal cells.
Aliases: ATP8A1 antibody, ATPIAPhospholipid-transporting ATPase IA antibody, EC 7.6.2.1 antibody, ATPase class I type 8A member 1 antibody, Chromaffin granule ATPase II antibody, P4-ATPase flippase complex alpha subunit ATP8A1 antibody
- UniProt
- Q9Y2Q0
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