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ATP8A1 抗体 (Internal Region)

ATP8A1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6260139
发货至: 中国
  • 抗原 See all ATP8A1 抗体
    ATP8A1 (ATPase, Class I, Type 8A, Member 1 (ATP8A1))
    抗原表位
    Internal Region
    适用
    人, 小鼠, 大鼠
    宿主
    • 7
    克隆类型
    • 7
    多克隆
    标记
    • 3
    • 2
    • 1
    • 1
    This ATP8A1 antibody is un-conjugated
    应用范围
    • 6
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    ATP8A1 Antibody detects endogenous levels of total ATP8A1.
    预测反应
    Pig,Bovine,Sheep,Rabbit,Dog,Chicken,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human ATP8A1, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product ATP8A1 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    ATP8A1 (ATPase, Class I, Type 8A, Member 1 (ATP8A1))
    别名
    ATP8A1 (ATP8A1 产品)
    别名
    ATPASEII antibody, ATPIA antibody, ATPP2 antibody, AI481521 antibody, AI853962 antibody, APLT antibody, AW743152 antibody, AW822227 antibody, Atp3a2 antibody, B230107D19Rik antibody, ClassI antibody, mKIAA4233 antibody, ATPase phospholipid transporting 8A1 antibody, ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 antibody, Atp8a1 antibody, ATP8A1 antibody
    背景

    Description: Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. In vitro, its ATPase activity is selectively and stereospecifically stimulated by phosphatidylserine (PS). The flippase complex ATP8A1:TMEM30A seems to play a role in regulation of cell migration probably involving flippase-mediated translocation of phosphatidylethanolamine (PE) at the plasma membrane. Acts as aminophospholipid translocase at the plasma membrane in neuronal cells.

    Gene: ATP8A1

    分子量
    120 kDa
    基因ID
    10396
    UniProt
    Q9Y2Q0
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