KAT2B 抗体 (AA 767-832)
Quick Overview for KAT2B 抗体 (AA 767-832) (ABIN7155270)
抗原
See all KAT2B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 767-832
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Histone acetyltransferase KAT2B protein (767-832AA)
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亚型
- IgG
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应用备注
- Recommended dilution: IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))
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别名
- KAT2B
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背景
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Background: Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Has significant histone acetyltransferase activity with core histones (H3 and H4), and also with nucleosome core particles. Also acetylates non-histone proteins, such as ACLY. Inhibits cell-cycle progression and counteracts the mitogenic activity of the adenoviral oncoprotein E1A. In case of HIV-1 infection, it is recruited by the viral protein Tat. Regulates Tat\'s transactivating activity and may help inducing chromatin remodeling of proviral genes. Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators: NPAS2-ARNTL/BMAL1 and CLOCK-ARNTL/BMAL1 heterodimers.
Aliases: CAF antibody, CREBBP associated factor antibody, GCN5 antibody, GCN5L antibody, GCN5L1 antibody, Histone acetylase PCAF antibody, Histone acetyltransferase KAT2B antibody, Histone acetyltransferase PCAF antibody, K(lysine) acetyltransferase 2B antibody, KAT2B antibody, KAT2B_HUMAN antibody, Lysine acetyltransferase 2B antibody, P antibody, P/CAF antibody, p300/CBP associated factor antibody, P300/CBP-associated factor antibody, Pcaf antibody
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UniProt
- Q92831
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途径
- p53 Pathway, Regulation of Carbohydrate Metabolic Process
抗原
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