CHAC1 抗体 (AA 43-264) (Biotin)
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- 抗原 See all CHAC1 抗体
- CHAC1 (ChaC, Cation Transport Regulator Homolog 1 (CHAC1))
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抗原表位
- AA 43-264
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CHAC1 antibody is conjugated to Biotin
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应用范围
- ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Glutathione-specific gamma-glutamylcyclotransferase 1 protein (43-264AA)
- 亚型
- IgG
- Top Product
- Discover our top product CHAC1 Primary Antibody
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anti-ChaC, Cation Transport Regulator Homolog 1 (CHAC1) (AA 131-222) antibody
CHAC1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-ChaC, Cation Transport Regulator Homolog 1 (CHAC1) (AA 43-264) antibodyCHAC1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ChaC, Cation Transport Regulator Homolog 1 (CHAC1) (C-Term) antibodyCHAC1 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-ChaC, Cation Transport Regulator Homolog 1 (CHAC1) (Internal Region) antibodyCHAC1 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-ChaC, Cation Transport Regulator Homolog 1 (CHAC1) (AA 188-237) antibodyCHAC1 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 兔, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- CHAC1 (ChaC, Cation Transport Regulator Homolog 1 (CHAC1))
- 别名
- CHAC1 (CHAC1 产品)
- 别名
- 1810008K03Rik antibody, RGD1307153 antibody, ChaC glutathione specific gamma-glutamylcyclotransferase 1 antibody, ChaC, cation transport regulator 1 antibody, ChaC glutathione-specific gamma-glutamylcyclotransferase 1 antibody, CHAC1 antibody, Chac1 antibody
- 背景
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Background: Catalyzes the cleavage glutathione into 5-oxoproline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides. Glutathione depletion is an important factor for apoptosis initiation and execution (PubMed:23070364). Acts as a pro-apoptotic component of the unfolded protein response pathway by mediating the pro-apoptotic effects of the ATF4-ATF3-DDIT3/CHOP cascade (PubMed:19109178). Negative regulator of Notch signaling pathway involved in embryonic neurogenesis: acts by inhibiting Notch cleavage by furin, maintaining Notch in an immature inactive form, thereby promoting neurogenesis in embryos (PubMed:22445366).
Aliases: Blocks Notch protein antibody, Botch antibody, Cation transport regulator like protein 1 antibody, Cation transport regulator-like protein 1 antibody, ChaC antibody, ChaC cation transport regulator homolog 1 antibody, ChaC cation transport regulator like 1 antibody, chac1 antibody, CHAC1_HUMAN antibody, Gamma GCT acting on glutathione homolog 1 antibody, Gamma-GCG 1 antibody, Glutathione-specific gamma-glutamylcyclotransferase 1 antibody
- UniProt
- Q9BUX1
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