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- 抗原 See all CHAC1 抗体
- CHAC1 (ChaC, Cation Transport Regulator Homolog 1 (CHAC1))
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抗原表位
- Internal Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CHAC1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- CHAC1 Antibody detects endogenous levels of total CHAC1.
- 预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human CHAC1, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product CHAC1 Primary Antibody
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anti-ChaC, Cation Transport Regulator Homolog 1 (CHAC1) (AA 131-222) antibody
CHAC1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-ChaC, Cation Transport Regulator Homolog 1 (CHAC1) (AA 43-264) antibodyCHAC1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ChaC, Cation Transport Regulator Homolog 1 (CHAC1) (C-Term) antibodyCHAC1 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-ChaC, Cation Transport Regulator Homolog 1 (CHAC1) (AA 188-237) antibodyCHAC1 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 兔, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- CHAC1 (ChaC, Cation Transport Regulator Homolog 1 (CHAC1))
- 别名
- CHAC1 (CHAC1 产品)
- 别名
- 1810008K03Rik antibody, RGD1307153 antibody, ChaC glutathione specific gamma-glutamylcyclotransferase 1 antibody, ChaC, cation transport regulator 1 antibody, ChaC glutathione-specific gamma-glutamylcyclotransferase 1 antibody, CHAC1 antibody, Chac1 antibody
- 背景
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Description: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides (PubMed:27913623). Glutathione depletion is an important factor for apoptosis initiation and execution. Acts as a pro-apoptotic component of the unfolded protein response pathway by mediating the pro-apoptotic effects of the ATF4-ATF3-DDIT3/CHOP cascade (PubMed:19109178). Negative regulator of Notch signaling pathway involved in embryonic neurogenesis: acts by inhibiting Notch cleavage by furin, maintaining Notch in an immature inactive form, thereby promoting neurogenesis in embryos (PubMed:22445366).
Gene: CHAC1
- 分子量
- 29kDa
- 基因ID
- 79094
- UniProt
- Q9BUX1
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