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- 抗原 See all STT3B 抗体
- STT3B (STT3, Subunit of The Oligosaccharyltransferase Complex, Homolog B (STT3B))
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抗原表位
- AA 682-809
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This STT3B antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B protein (682-809AA)
- 亚型
- IgG
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anti-STT3, Subunit of The Oligosaccharyltransferase Complex, Homolog B (STT3B) antibody
STT3B 适用: 人 IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-STT3, Subunit of The Oligosaccharyltransferase Complex, Homolog B (STT3B) (C-Term) antibodySTT3B 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: IHC:1:200-1:500,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- STT3B (STT3, Subunit of The Oligosaccharyltransferase Complex, Homolog B (STT3B))
- 别名
- STT3B (STT3B 产品)
- 别名
- RGD1311563 antibody, 1300006C19Rik antibody, Simp antibody, SIMP antibody, STT3-B antibody, STT3B, catalytic subunit of the oligosaccharyltransferase complex antibody, STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae) antibody, Stt3b antibody, STT3B antibody
- 背景
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Background: Catalytic subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). STT3B is present in a small subset of OST complexes and mediates both cotranslational and post-translational N-glycosylation of target proteins: STT3B-containing complexes are required for efficient post-translational glycosylation and while they are less competent than STT3A-containing complexes for cotranslational glycosylation, they have the ability to mediate glycosylation of some nascent sites that are not accessible for STT3A. STT3B-containing complexes also act post-translationally and mediate modification of skipped glycosylation sites in unfolded proteins. Plays a role in ER-associated degradation (ERAD) pathway that mediates ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins by mediating N-glycosylation of unfolded proteins, which are then recognized by the ERAD pathway and targeted for degradation. Mediates glycosylation of the disease variant AMYL-TTR \\\'Asp-38\\\' of TTR at \\\'Asn-118\\\', leading to its degradation.
Aliases: Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B antibody, Homolog of yeast STT3 antibody, Oligosaccharyl transferase subunit STT3B antibody, SIMP antibody, source of immunodominant MHC associated peptides antibody, Source of immunodominant MHC-associated peptides homolog antibody, STT3 subunit of the oligosaccharyltransferase complex homolog B (S. cerevisiae) antibody, STT3 subunit of the oligosaccharyltransferase complex homolog B antibody, STT3-B antibody, Stt3b antibody, STT3B_HUMAN antibody
- UniProt
- Q8TCJ2
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