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Retinoblastoma Binding Protein 8 抗体 (AA 126-331)

This 兔 多克隆 anti-Retinoblastoma Binding Protein 8 antibody specifically detects Retinoblastoma Binding Protein 8 in ELISA 和 IHC. The antibody is reactive with 人 samples.
产品编号 ABIN7150164
发货至: 中国
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Quick Overview for Retinoblastoma Binding Protein 8 抗体 (AA 126-331) (ABIN7150164)

抗原

See all Retinoblastoma Binding Protein 8 (RBBP8) 抗体
Retinoblastoma Binding Protein 8 (RBBP8)

适用

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宿主

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克隆类型

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多克隆

标记

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This Retinoblastoma Binding Protein 8 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    AA 126-331

    原理

    RBBP8 Antibody

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human DNA endonuclease RBBP8 protein (126-331AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    Retinoblastoma Binding Protein 8 (RBBP8)

    别名

    RBBP8

    背景

    Background: Endonuclease that cooperates with the MRE11-RAD50-NBN (MRN) complex in processing meiotic and mitotic double-strand breaks (DSBs) by ensuring both resection and intrachromosomal association of the broken ends. Functions downstream of the MRN complex and ATM, promotes ATR activation and its recruitment to DSBs in the S/G2 phase facilitating the generation of ssDNA. Component of the BRCA1-RBBP8 complex that regulates CHEK1 activation and controls cell cycle G2/M checkpoints on DNA damage. Promotes microhomology-mediated alternative end joining (A-NHEJ) during class-switch recombination and plays an essential role in chromosomal translocations.

    Aliases: COM1 antibody, COM1_HUMAN antibody, CtBP interacting protein antibody, CtBP-interacting protein antibody, CtIP antibody, DNA endonuclease RBBP8 antibody, JWDS antibody, RB binding protein 8 endonuclease antibody, RBBP-8 antibody, RBBP8 antibody, Retinoblastoma-binding protein 8 antibody, Retinoblastoma-interacting protein and myosin-like antibody, Rim antibody, SAE2 antibody, SCKL2 antibody, Sporulation in the absence of SPO11 protein 2 homolog antibody

    UniProt

    Q99708

    途径

    Cell Division Cycle, DNA Damage Repair
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