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DIABLO 抗体 (AA 168-236) (FITC)

This FITC-conjugated 兔 多克隆 anti-DIABLO antibody specifically detects DIABLO in not_set. The antibody is reactive with 人 samples.
产品编号 ABIN7149842
发货至: 中国
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Quick Overview for DIABLO 抗体 (AA 168-236) (FITC) (ABIN7149842)

抗原

See all DIABLO 抗体
DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))

适用

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宿主

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克隆类型

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多克隆

标记

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This DIABLO antibody is conjugated to FITC

应用范围

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  • 抗原表位

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    AA 168-236

    原理

    DIABLO Antibody, FITC conjugated

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human Diablo homolog, mitochondrial protein (168-236AA)

    亚型

    IgG
  • 限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))

    别名

    DIABLO

    背景

    Background: Promotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway. Acts by opposing the inhibitory activity of inhibitor of apoptosis proteins (IAP). Inhibits the activity of BIRC6/bruce by inhibiting its binding to caspases. Isoform 3 attenuates the stability and apoptosis-inhibiting activity of XIAP/BIRC4 by promoting XIAP/BIRC4 ubiquitination and degradation through the ubiquitin-proteasome pathway. Isoform 3 also disrupts XIAP/BIRC4 interacting with processed caspase-9 and promotes caspase-3 activation. Isoform 1 is defective in the capacity to down-regulate the XIAP/BIRC4 abundance.

    Aliases: 0610041G12Rik antibody, DBLOH_HUMAN antibody, DBOH antibody, DFNA64 antibody, diablo antibody, Diablo homolog (Drosophila) antibody, Diablo homolog antibody, Diablo homolog mitochondrial antibody, Diablo IAP binding mitochondrial protein antibody, Diablo like protein antibody, DIABLO S antibody, Direct IAP binding protein with low pI antibody, Direct IAP-binding protein with low pI antibody, FLJ10537 antibody, FLJ25049 antibody, mitochondrial antibody, Mitochondrial Smac protein antibody, Second mitochondria derived activator of caspase antibody, Second mitochondria-derived activator of caspase antibody, second mitochondrial activator of caspases antibody, SMAC 3 antibody, Smac antibody, Smac protein antibody, SMAC3 antibody

    UniProt

    Q9NR28

    途径

    Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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