电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

DIABLO 抗体 (AA 168-236) (Biotin)

This anti-DIABLO antibody is a 兔 多克隆 antibody detecting DIABLO in ELISA. Suitable for 人.
产品编号 ABIN7149841
发货至: 中国

Quick Overview for DIABLO 抗体 (AA 168-236) (Biotin) (ABIN7149841)

抗原

See all DIABLO 抗体
DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))

适用

  • 62
  • 28
  • 27
  • 3
  • 2
  • 2
  • 2
  • 1

宿主

  • 54
  • 10
  • 1

克隆类型

  • 44
  • 21
多克隆

标记

  • 41
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
This DIABLO antibody is conjugated to Biotin

应用范围

  • 41
  • 21
  • 18
  • 8
  • 7
  • 7
  • 7
  • 5
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
ELISA
  • 抗原表位

    • 11
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 168-236

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Diablo homolog, mitochondrial protein (168-236AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))

    别名

    DIABLO

    背景

    Background: Promotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway. Acts by opposing the inhibitory activity of inhibitor of apoptosis proteins (IAP). Inhibits the activity of BIRC6/bruce by inhibiting its binding to caspases. Isoform 3 attenuates the stability and apoptosis-inhibiting activity of XIAP/BIRC4 by promoting XIAP/BIRC4 ubiquitination and degradation through the ubiquitin-proteasome pathway. Isoform 3 also disrupts XIAP/BIRC4 interacting with processed caspase-9 and promotes caspase-3 activation. Isoform 1 is defective in the capacity to down-regulate the XIAP/BIRC4 abundance.

    Aliases: 0610041G12Rik antibody, DBLOH_HUMAN antibody, DBOH antibody, DFNA64 antibody, diablo antibody, Diablo homolog (Drosophila) antibody, Diablo homolog antibody, Diablo homolog mitochondrial antibody, Diablo IAP binding mitochondrial protein antibody, Diablo like protein antibody, DIABLO S antibody, Direct IAP binding protein with low pI antibody, Direct IAP-binding protein with low pI antibody, FLJ10537 antibody, FLJ25049 antibody, mitochondrial antibody, Mitochondrial Smac protein antibody, Second mitochondria derived activator of caspase antibody, Second mitochondria-derived activator of caspase antibody, second mitochondrial activator of caspases antibody, SMAC 3 antibody, Smac antibody, Smac protein antibody, SMAC3 antibody

    UniProt

    Q9NR28

    途径

    Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
You are here:
Chat with us!