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NFKBIE 抗体 (pSer157)

NFKBIE 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN710726
发货至: 中国
  • 抗原 See all NFKBIE 抗体
    NFKBIE (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, epsilon (NFKBIE))
    抗原表位
    • 25
    • 15
    • 14
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer157
    适用
    • 69
    • 49
    • 22
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 83
    • 2
    克隆类型
    • 75
    • 10
    多克隆
    标记
    • 29
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    This NFKBIE antibody is un-conjugated
    应用范围
    • 71
    • 38
    • 38
    • 21
    • 15
    • 11
    • 8
    • 6
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    预测反应
    Human,Cow
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic phosphopeptide derived from human NFKBIE around the phosphorylation site of Ser157
    亚型
    IgG
    Top Product
    Discover our top product NFKBIE Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    NFKBIE (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, epsilon (NFKBIE))
    别名
    Ikb epsilon (NFKBIE 产品)
    别名
    NFKBIE antibody, IKBE antibody, Slc35b2 antibody, NFKB inhibitor epsilon antibody, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon antibody, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon antibody, NFKBIE antibody, Nfkbie antibody
    背景

    Synonyms: NFKBIE phospho S157, IKB epsilon Ser157, IKB epsilon S, p-IKB epsilon Ser157, p-IKB epsilon S157, I kappa B epsilon, IkappaBepsilon, IkB E, IKBE, IKB epsilon, MGC72568, NF kappa B inhibitor epsilon, NF kappa BIE, NFkappa BIE, NFkappaB inhibitor epsilon, NFKBIE, Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor epsilon, OTTHUMP00000016522, Slc35b2, solute carrier family 35, member B2.

    Background: NFKB1 or NFKB2 is bound to REL, RELA, or RELB to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, or IKBKB) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T, R is an A or G purine, and Y is a C or T pyrimidine). For some genes, activation requires NFKB interaction with other transcription factors, such as STAT, AP1 (JUN), and NFAT.

    基因ID
    4794
    途径
    NF-kappaB Signaling, Maintenance of Protein Location
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