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Casein Kinase 1 gamma 2 抗体 (Isoform gamma 2)

CSNK1G2 适用: 人 WB, IHC, ELISA, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7146876
发货至: 中国
  • 抗原 See all Casein Kinase 1 gamma 2 (CSNK1G2) 抗体
    Casein Kinase 1 gamma 2 (CSNK1G2) (Casein Kinase 1, gamma 2 (CSNK1G2))
    抗原表位
    • 15
    • 8
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 316-415, Isoform gamma 2
    适用
    • 43
    • 40
    • 17
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    宿主
    • 49
    • 7
    克隆类型
    • 50
    • 6
    多克隆
    标记
    • 30
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Casein Kinase 1 gamma 2 antibody is un-conjugated
    应用范围
    • 48
    • 18
    • 14
    • 14
    • 14
    • 9
    • 7
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)
    交叉反应
    人, 小鼠
    纯化方法
    Antigen Affinity Purified
    免疫原
    Recombinant Human Casein kinase I isoform gamma-2 protein (316-415AA)
    亚型
    IgG
  • 应用备注
    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IP:1:200-1:2000,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    Casein Kinase 1 gamma 2 (CSNK1G2) (Casein Kinase 1, gamma 2 (CSNK1G2))
    别名
    CSNK1G2 (CSNK1G2 产品)
    别名
    CK1g2 antibody, 2810429I12Rik antibody, AI463719 antibody, CKI antibody, ck1-gamma antibody, CSNK1G2 antibody, ck1g2 antibody, csnk1g2 antibody, fj97g11 antibody, wu:fj97g11 antibody, wz8345 antibody, zgc:110719 antibody, zgc:153415 antibody, casein kinase 1 gamma 2 antibody, casein kinase 1, gamma 2 antibody, casein kinase 1 gamma 2 L homeolog antibody, casein kinase 1, gamma 2a antibody, casein kinase 1, gamma 2b antibody, CSNK1G2 antibody, Csnk1g2 antibody, csnk1g2.L antibody, csnk1g2 antibody, csnk1g2a antibody, csnk1g2b antibody
    背景

    Background: Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates COL4A3BP/CERT, MTA1 and SMAD3. Involved in brain development and vesicular trafficking and neurotransmitter releasing from small synaptic vesicles. Regulates fast synaptic transmission mediated by glutamate. SMAD3 phosphorylation promotes its ligand-dependent ubiquitination and subsequent proteasome degradation, thus inhibiting SMAD3-mediated TGF-beta responses. Hyperphosphorylation of the serine-repeat motif of COL4A3BP/CERT leads to its inactivation by dissociation from the Golgi complex, thus down-regulating ER-to-Golgi transport of ceramide and sphingomyelin synthesis. Triggers PER1 proteasomal degradation probably through phosphorylation.

    Aliases: Casein kinase 1, gamma 2 antibody, Casein kinase I isoform gamma 2 antibody, Casein kinase I isoform gamma-2 antibody, CK1g2 antibody, CKI gamma 2 antibody, CKI-gamma 2 antibody, CSNK1G 2 antibody, Csnk1g2 antibody, KC1G2_HUMAN antibody

    UniProt
    P78368
    途径
    Hedgehog Signaling
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