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Casein Kinase 1 delta 抗体 (Isoform delta)

CSNK1D 适用: 人 WB, ELISA, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7146858
发货至: 中国
  • 抗原 See all Casein Kinase 1 delta (CSNK1D) 抗体
    Casein Kinase 1 delta (CSNK1D) (Casein Kinase 1, delta (CSNK1D))
    抗原表位
    • 10
    • 8
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    • 5
    • 5
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    • 1
    • 1
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    AA 152-398, Isoform delta
    适用
    • 47
    • 26
    • 12
    • 4
    • 3
    • 3
    • 3
    • 3
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    • 2
    • 2
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    • 1
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    宿主
    • 53
    • 4
    • 1
    • 1
    克隆类型
    • 56
    • 3
    多克隆
    标记
    • 31
    • 5
    • 5
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    • 1
    • 1
    • 1
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    This Casein Kinase 1 delta antibody is un-conjugated
    应用范围
    • 43
    • 31
    • 15
    • 7
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Casein kinase I isoform delta protein (152-398AA)
    亚型
    IgG
  • 应用备注
    Recommended dilution: WB:1:1000-1:5000, IHC:1:1000-1:2000, IF:1:200-1:500, IP:1:200-1:2000,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    Casein Kinase 1 delta (CSNK1D) (Casein Kinase 1, delta (CSNK1D))
    别名
    CSNK1D (CSNK1D 产品)
    别名
    ASPS antibody, CKIdelta antibody, FASPS2 antibody, HCKID antibody, 1200006A05Rik antibody, AA409348 antibody, D930010H05Rik antibody, CKI-delta antibody, CKId antibody, csnk1d antibody, wu:fb69b03 antibody, wu:fj97a05 antibody, zgc:77627 antibody, CSNK1D antibody, ckIdelta antibody, Csnk1d antibody, csnk1dl antibody, wu:fb50c04 antibody, zgc:63971 antibody, casein kinase 1 delta antibody, casein kinase 1, delta antibody, casein kinase 1, delta b antibody, casein kinase 1 delta S homeolog antibody, casein kinase 1, delta a antibody, CSNK1D antibody, Csnk1d antibody, csnk1d antibody, csnk1db antibody, Bm1_37175 antibody, csnk1d.S antibody, csnk1da antibody
    背景

    Background: Essential serine/threonine-protein kinase that regulates diverse cellular growth and survival processes including Wnt signaling, DNA repair and circadian rhythms. It can phosphorylate a large number of proteins. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Phosphorylates connexin-43/GJA1, MAP1A, SNAPIN, MAPT/TAU, TOP2A, DCK, HIF1A, EIF6, p53/TP53, DVL2, DVL3, ESR1, AIB1/NCOA3, DNMT1, PKD2, YAP1, PER1 and PER2. Central component of the circadian clock. In balance with PP1, determines the circadian period length through the regulation of the speed and rhythmicity of PER1 and PER2 phospohorylation. Controls PER1 and PER2 nuclear transport and degradation. YAP1 phosphorylation promotes its SCF(beta-TRCP) E3 ubiquitin ligase-mediated ubiquitination and subsequent degradation. DNMT1 phosphorylation reduces its DNA-binding activity. Phosphorylation of ESR1 and AIB1/NCOA3 stimulates their activity and coactivation. Phosphorylation of DVL2 and DVL3 regulates WNT3A signaling pathway that controls neurite outgrowth. EIF6 phosphorylation promotes its nuclear export. Triggers down-regulation of dopamine receptors in the forebrain. Activates DCK in vitro by phosphorylation. TOP2A phosphorylation favors DNA cleavable complex formation. May regulate the formation of the mitotic spindle apparatus in extravillous trophoblast. Modulates connexin-43/GJA1 gap junction assembly by phosphorylation. Probably involved in lymphocyte physiology. Regulates fast synaptic transmission mediated by glutamate.

    Aliases: Casein Kinase 1 delta antibody, Casein kinase I delta isoform antibody, Casein kinase I isoform delta antibody, CKI delta antibody, CKI-delta antibody, CKId antibody, CKIdelta antibody, CSNK 1D antibody, CSNK1D antibody, HCKID antibody, KC1D_HUMAN antibody, Protein kinase CK1 delta antibody

    UniProt
    P48730
    途径
    Hedgehog Signaling, M Phase
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