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- 抗原 See all TAP1 抗体
- TAP1 (Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP1))
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抗原表位
- AA 524-808
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TAP1 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human Antigen peptide transporter 1 protein (524-808AA)
- 亚型
- IgG
- Top Product
- Discover our top product TAP1 Primary Antibody
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anti-Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP1) antibody
TAP1 适用: 人, 大鼠 WB, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP1) (AA 501-600) antibodyTAP1 适用: 人, Pig WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP1) antibodyTAP1 适用: 人 WB, ELISA, IP, IF, ICC 宿主: 小鼠 Monoclonal 53H8 unconjugated
anti-Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP1) (AA 241-350) antibodyTAP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1B11 unconjugated
anti-Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP1) (AA 241-350) antibodyTAP1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3D4 unconjugated
anti-Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP1) (AA 525-808) antibodyTAP1 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP1) (Middle Region) antibodyTAP1 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP1) (AA 765-794) antibodyTAP1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP1) (Internal Region) antibodyVerified TAP1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP1) (AA 524-808) antibodyTAP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- TAP1 (Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP1))
- 别名
- TAP1 (TAP1 产品)
- 别名
- ABC17 antibody, ABCB2 antibody, APT1 antibody, D6S114E antibody, PSF-1 antibody, PSF1 antibody, RING4 antibody, TAP1*0102N antibody, TAP1N antibody, abc17 antibody, abcb2 antibody, apt1 antibody, psf1 antibody, ring4 antibody, tap1a antibody, tap1n antibody, Abcb2 antibody, Ham-1 antibody, Ham1 antibody, MTP1 antibody, TAP antibody, Tap-1 antibody, Y3 antibody, Cim antibody, transporter 1, ATP binding cassette subfamily B member antibody, transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) L homeolog antibody, transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) antibody, TAP1 antibody, tap1.L antibody, Tap1 antibody
- 背景
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Background: Involved in the transport of antigens from the cytoplasm to the endoplasmic reticulum for association with MHC class I molecules. Also acts as a molecular scaffold for the final stage of MHC class I folding, namely the binding of peptide. Nascent MHC class I molecules associate with TAP via tapasin. Inhibited by the covalent attachment of herpes simplex virus ICP47 protein, which blocks the peptide-binding site of TAP. Inhibited by human cytomegalovirus US6 glycoprotein, which binds to the lumenal side of the TAP complex and inhibits peptide translocation by specifically blocking ATP-binding to TAP1 and prevents the conformational rearrangement of TAP induced by peptide binding. Inhibited by human adenovirus E3-19K glycoprotein, which binds the TAP complex and acts as a tapasin inhibitor, preventing MHC class I/TAP association. Expression of TAP1 is down-regulated by human Epstein-Barr virus vIL-10 protein, thereby affecting the transport of peptides into the endoplasmic reticulum and subsequent peptide loading by MHC class I molecules.
Aliases: ABC 17 antibody, ABC transporter MHC 1 antibody, ABC17 antibody, ABCB 2 antibody, ABCB2 antibody, Antigen peptide transporter 1 antibody, APT 1 antibody, APT1 antibody, ATP binding cassette sub family B (MDR/TAP) member 2 antibody, ATP binding cassette sub family B member 2 antibody, ATP binding cassette transporter antibody, ATP-binding cassette sub-family B member 2 antibody, D6S114E antibody, FLJ26666 antibody, FLJ41500 antibody, Peptide supply factor 1 antibody, Peptide transporter involved in antigen processing 1 antibody, Peptide transporter PSF 1 antibody, Peptide transporter PSF1 antibody, Peptide transporter TAP 1 antibody, Peptide transporter TAP1 antibody, PSF 1 antibody, PSF-1 antibody, PSF1 antibody, Really interesting new gene 4 protein antibody, RING 4 antibody, RING4 antibody, TAP 1 antibody, TAP1 antibody, TAP1*0102N antibody, TAP1_HUMAN antibody, TAP1N antibody, Transporter 1 ATP binding cassette sub family B (MDR/TAP) antibody, Transporter 1 ATP binding cassette sub family B antibody, Transporter associated with antigen processing antibody, Transporter ATP binding cassette major histocompatibility complex 1 antibody, Y3 antibody
- UniProt
- Q03518
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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