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TAP1 产品

(Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP1))
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is involved in the pumping of degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. [provided by RefSeq, Jul 2008].

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Featured TAP1 Categories

TAP1 抗体

High quality antibodies with extensive validation data.

TAP1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

TAP1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TAP1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Rat
Application WB, IP, IHC (p)
Validations
  • (4)
Cat. No. ABIN7211386
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7144328
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Pig
Application WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (1)
  • (1)
Cat. No. ABIN680728
Quantity 100 μL
Datasheet Datasheet

Recommended TAP1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6960151
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1504005
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1504006
Quantity 96 tests
Datasheet Datasheet

Recommended TAP1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1322140
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1322142
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3133321
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our TAP1 Products

Stettner, Lohmann, Wolffram, Weinberger, Dehmel, Hartung, Mausberg, Kieseier: "Interleukin-17 impedes Schwann cell-mediated myelination." in: Journal of neuroinflammation, Vol. 11, pp. 63, (2014) (PubMed).

Dervovic, Liang, Cannons, Elford, Mohtashami, Ohashi, Schwartzberg, Zúñiga-Pflücker: "Cellular and molecular requirements for the selection of in vitro-generated CD8 T cells reveal a role for Notch." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 4, pp. 1704-15, (2013) (PubMed).

Lajoie, Zijenah, Faucher, Ward, Roger: "Novel TAP1 polymorphisms in indigenous Zimbabweans: their potential implications on TAP function and in human diseases." in: Human immunology, Vol. 64, Issue 8, pp. 823-9, (2003) (PubMed).

Kim, Kataoka, Dreyfuss: "Role of the nonsense-mediated decay factor hUpf3 in the splicing-dependent exon-exon junction complex." in: Science (New York, N.Y.), Vol. 293, Issue 5536, pp. 1832-6, (2001) (PubMed).

Tang, Freedman, Allen, Karita, Musonda, Braga, Margolick, Kaslow: "TAPI polymorphisms in several human ethnic groups: characteristics, evolution, and genotyping strategies." in: Human immunology, Vol. 62, Issue 3, pp. 256-68, (2001) (PubMed).

Gaudet, Wiley: "Structure of the ABC ATPase domain of human TAP1, the transporter associated with antigen processing." in: The EMBO journal, Vol. 20, Issue 17, pp. 4964-72, (2001) (PubMed).

Synonyms and alternative names related to TAP1

transporter 1, ATP binding cassette subfamily B member (TAP1), transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) L homeolog (tap1.L), transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) (TAP1), transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) (Tap1), transporter 1, ATP binding cassette subfamily B member (Tap1), ABC17, abc17, ABCB2, abcb2, Abcb2, APT1, apt1, Cim, D6S114E, Ham-1, Ham1, MTP1, PSF-1, PSF1, psf1, RING4, ring4, TAP, Tap-1, TAP1*0102N, tap1a, TAP1N, tap1n, Y3

Protein level used designations for TAP1

  • ABC transporter, MHC 1
  • ATP-binding cassette sub-family B member 2
  • ATP-binding cassette, sub-family B (MDR/TAP), member 2
  • antigen peptide transporter 1
  • peptide supply factor 1
  • peptide transporter PSF1
  • peptide transporter TAP1
  • peptide transporter involved in antigen processing 1
  • really interesting new gene 4 protein
  • transporter associated with antigen processing
  • transporter, ATP-binding cassette, major histocompatibility complex, 1
  • transporter associated with antigen processing 1a
  • transporter associated with antigen presentation 1
  • transporter associated with antigen processing 1
  • transporter 1 ATP-binding cassette sub-family B
  • ABC transporter, MHC, 1
  • ATP dependent transport protein family member
  • ATP-binding cassette transporter, major histocompatibility complex, 1
  • histocompatibility antigen modifier 1
  • transporter 1, ABC (ATP binding cassette)
  • transporter, ABC, MHC, 1
  • APT1
  • transporter 1 ABC (ATP binding cassette)
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