PSMD14 抗体 (Regulatory Subunit 14)
-
- 抗原 See all PSMD14 抗体
- PSMD14 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 14 (PSMD14))
-
抗原表位
- AA 264-283, Regulatory Subunit 14
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This PSMD14 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人, 大鼠
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Peptide sequence from Human 26S proteasome non-ATPase regulatory subunit 14 protein (264-283AA)
- 亚型
- IgG
- Top Product
- Discover our top product PSMD14 Primary Antibody
-
anti-Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 14 (PSMD14) (Center) antibody
PSMD14 适用: 人 WB, IF, IP, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 14 (PSMD14) antibodyPSMD14 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 14 (PSMD14) antibodyPSMD14 适用: 人 IF, IP, ICC, FACS 宿主: 小鼠 Monoclonal 9B10 unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 14 (PSMD14) (AA 362-632) antibodyPSMD14 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 14 (PSMD14) (AA 1-95) antibodyPSMD14 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4A10-E8 unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 14 (PSMD14) (AA 1-310) antibodyPSMD14 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 14 (PSMD14) (AA 160-300) antibodyPSMD14 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 14 (PSMD14) (C-Term) antibodyPSMD14 适用: 人, 小鼠, 大鼠, 斑马鱼, Cow, 马, 豚鼠, 兔, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 14 (PSMD14) (N-Term) antibodyPSMD14 适用: 人, 小鼠, 大鼠, 斑马鱼, Cow, 马, 豚鼠, 兔, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 14 (PSMD14) (AA 1-95) antibodyPSMD14 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
-
- 应用备注
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- 抗原
- PSMD14 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 14 (PSMD14))
- 别名
- PSMD14 (PSMD14 产品)
- 别名
- PAD1 antibody, POH1 antibody, RPN11 antibody, 2610312C03Rik antibody, 3200001M20Rik antibody, AA986732 antibody, Pad1 antibody, Poh1 antibody, rpm11 antibody, zgc:162272 antibody, proteasome 26S subunit, non-ATPase 14 antibody, proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 antibody, 26S proteasome non-ATPase regulatory subunit 14 antibody, proteasome 26S subunit, non-ATPase 14 L homeolog antibody, 26S proteasome-associated pad1 homolog antibody, PSMD14 antibody, Psmd14 antibody, rpn-11 antibody, psmd14 antibody, psmd14.L antibody
- 背景
-
Background: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. The PSMD14 subunit is a metalloprotease that specifically cleaves \\\'Lys-63\\\'-linked polyubiquitin chains within the complex. Plays a role in response to double-strand breaks (DSBs): acts as a regulator of non-homologous end joining (NHEJ) by cleaving \\\'Lys-63\\\'-linked polyubiquitin, thereby promoting retention of JMJD2A/KDM4A on chromatin and restricting TP53BP1 accumulation. Also involved in homologous recombination repair by promoting RAD51 loading.
Aliases: 26S proteasome non-ATPase regulatory subunit 14 antibody, 26S proteasome regulatory subunit rpn11 antibody, 26S proteasome-associated PAD1 homolog 1 antibody, 26S proteasome-associated PAD1 homolog antibody, PAD1 antibody, PAD1, yeast, homolog of antibody, POH1 antibody, Proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 antibody, Proteasome 26S subunit non ATPase 14 antibody, PSDE_HUMAN antibody, Psmd14 antibody, RPN11 antibody, Testis tissue sperm binding protein Li 69n antibody
- UniProt
- O00487
- 途径
- Mitotic G1-G1/S Phases, DNA Replication, M Phase, Positive Regulation of Endopeptidase Activity, Synthesis of DNA, Ubiquitin Proteasome Pathway
-
