电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

PSMD14 抗体 (Center)

PSMD14 适用: 人 WB, IF, IP, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2856031
发货至: 中国
  • 抗原 See all PSMD14 抗体
    PSMD14 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 14 (PSMD14))
    抗原表位
    • 15
    • 15
    • 10
    • 10
    • 9
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    适用
    • 87
    • 30
    • 27
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    宿主
    • 79
    • 8
    克隆类型
    • 79
    • 8
    多克隆
    标记
    • 38
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This PSMD14 antibody is un-conjugated
    应用范围
    • 53
    • 35
    • 26
    • 26
    • 14
    • 9
    • 9
    • 6
    • 6
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    产品特性
    Rabbit Polyclonal antibody to MAD1 (MAD1 mitotic arrest deficient-like 1 (yeast))
    MAD1 antibody
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human MAD1. The exact sequence is proprietary.
    亚型
    IgG
  • 应用备注
    Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Immunoprecipitation 1:100-1:500* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Immunoprecipitation1:100-1:500* Western blot1:500-1:3000*
    说明

    Positive Control: 293T , A431 , HeLa , HepG2 , A375

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    1XPBS, 1 % BSA, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Alfonso-Pérez, Hayward, Holder, Gruneberg, Barr: "MAD1-dependent recruitment of CDK1-CCNB1 to kinetochores promotes spindle checkpoint signaling." in: The Journal of cell biology, Vol. 218, Issue 4, pp. 1108-1117, (2020) (PubMed).

  • 抗原
    PSMD14 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 14 (PSMD14))
    别名
    MAD1 (PSMD14 产品)
    别名
    PAD1 antibody, POH1 antibody, RPN11 antibody, 2610312C03Rik antibody, 3200001M20Rik antibody, AA986732 antibody, Pad1 antibody, Poh1 antibody, rpm11 antibody, zgc:162272 antibody, proteasome 26S subunit, non-ATPase 14 antibody, proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 antibody, 26S proteasome non-ATPase regulatory subunit 14 antibody, proteasome 26S subunit, non-ATPase 14 L homeolog antibody, 26S proteasome-associated pad1 homolog antibody, PSMD14 antibody, Psmd14 antibody, rpn-11 antibody, psmd14 antibody, psmd14.L antibody
    背景
    MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Three transcript variants encoding the same protein have been found for this gene.

    Cellular Localization: Nucleus , Kinetochore
    分子量
    83 kDa
    基因ID
    8379
    途径
    Mitotic G1-G1/S Phases, DNA Replication, M Phase, Positive Regulation of Endopeptidase Activity, Synthesis of DNA, Ubiquitin Proteasome Pathway
You are here:
客服