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TYK2 抗体 (pTyr1054)

TYK2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7138907
发货至: 中国
  • 抗原 See all TYK2 抗体
    TYK2 (Tyrosine Kinase 2 (TYK2))
    抗原表位
    • 18
    • 16
    • 15
    • 8
    • 7
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr1054
    适用
    • 77
    • 29
    • 22
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 72
    • 5
    克隆类型
    • 72
    • 6
    多克隆
    标记
    • 35
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This TYK2 antibody is un-conjugated
    应用范围
    • 61
    • 37
    • 20
    • 13
    • 13
    • 13
    • 10
    • 6
    • 4
    • 2
    • 2
    Western Blotting (WB), ELISA
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
    免疫原
    Peptide sequence around phosphorylation site of tyrosine 1054 (H-E-Y(p)-Y-R) derived from Human TYK2.
    亚型
    IgG
    Top Product
    Discover our top product TYK2 Primary Antibody
  • 应用备注
    WB:1:500-1:1000,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    TYK2 (Tyrosine Kinase 2 (TYK2))
    别名
    TYK2 (TYK2 产品)
    别名
    JTK1 antibody, tyrosine kinase 2 antibody, TYK2 antibody, Tyk2 antibody
    背景

    Background:

    TYK2 encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.

    Zheng H, et al. (2005) Mol Cell Proteomics. 4(6):721-730.
    Gauzzi MC, et al. (1996) J Biol Chem. 271(34): 20494-20500.

    Aliases: JTK 1 antibody, JTK1 antibody, Non receptor tyrosine protein kinase 2 antibody, Non receptor tyrosine protein kinase TYK2 antibody, Non-receptor tyrosine-protein kinase TYK2 antibody, OTTHUMP00000232745 antibody, OTTHUMP00000232746 antibody, OTTHUMP00000232748 antibody, Protein Tyrosine Kinase 2 antibody, TYK 2 antibody, Tyk2 antibody, TYK2_HUMAN antibody, Tyrosine kinase 2 antibody

    UniProt
    P29597
    途径
    JAK/STAT Signaling, Hepatitis C
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