TYK2 抗体 (AA 1020-1069)
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Quick Overview for TYK2 抗体 (AA 1020-1069) (ABIN1533032)
抗原
See all TYK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1020-1069
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原理
- Tyk 2 Antibody
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特异性
- Tyk 2 Polyclonal Antibody detects endogenous levels of Tyk 2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human TYK2. AA range:1020-1069
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- TYK2 (Tyrosine Kinase 2 (TYK2))
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别名
- TYK2
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背景
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Synonyms: TYK2, Non-receptor tyrosine-protein kinase TYK2
Background: tyrosine kinase 2(TYK2) Homo sapiens This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq, Jul 2008],
Gene Name: TYK2
Protein Name: Non-receptor tyrosine-protein kinase TYK2
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分子量
- 133 kDa
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基因ID
- 7297
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OMIM
- 176941
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UniProt
- P29597
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途径
- JAK/STAT Signaling, Hepatitis C
抗原
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