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Retinoblastoma 1 抗体 (pSer608)

This 兔 多克隆 antibody specifically detects Retinoblastoma 1 in WB, IHC 和 ELISA. It exhibits reactivity toward 人.
产品编号 ABIN7138658
发货至: 中国
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Quick Overview for Retinoblastoma 1 抗体 (pSer608) (ABIN7138658)

抗原

See all Retinoblastoma 1 (RB1) 抗体
Retinoblastoma 1 (RB1)

适用

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宿主

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克隆类型

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  • 70
多克隆

标记

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This Retinoblastoma 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

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    pSer608

    原理

    Phospho-RB1 (Ser608) Antibody

    交叉反应

    小鼠

    纯化方法

    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

    免疫原

    Peptide sequence around phosphorylation site of Serine 608(Y-L-S(p)-P-V) derived from Human Retinoblastoma.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    Retinoblastoma 1 (RB1)

    别名

    RB1

    背景

    Background:

    Retinoblastoma (RB) is an embryonic malignant neoplasm of retinal origin. It almost always presents in early childhood and is often bilateral. Spontaneous regression ('cure') occurs in some cases.

    Lee W.-H., Nature 329:642-645(1987).
    Lee W.-H., Science 235:1394-1399(1987).
    Friend S.H., Proc. Natl. Acad. Sci. U.S.A. 84:9059-9063(1987).

    Aliases: Exon 17 tumor GOS561 substitution mutation causes premature stop antibody, GOS563 exon 17 substitution mutation causes premature stop antibody, OSRC antibody, Osteosarcoma antibody, p105-Rb antibody, P105RB antibody, PP105 antibody, pp110 antibody, PPP1R130 antibody, pRb antibody, Prepro retinoblastoma associated protein antibody, Protein phosphatase 1 regulatory subunit 130 antibody, Rb antibody, RB transcriptional corepressor 1 antibody, RB_HUMAN antibody, RB1 antibody, RB1 gene antibody, Retinoblastoma 1 antibody, Retinoblastoma suspectibility protein antibody, Retinoblastoma-associated protein antibody

    UniProt

    P06400

    途径

    Cell Division Cycle, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagy
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