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MEK1 抗体 (pSer217, pSer221)

This anti-MEK1 antibody is a 兔 多克隆 antibody detecting MEK1 in WB, IHC 和 ELISA. Suitable for 人.
产品编号 ABIN7138484
发货至: 中国

Quick Overview for MEK1 抗体 (pSer217, pSer221) (ABIN7138484)

抗原

See all MEK1 (MAP2K1) 抗体
MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))

适用

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宿主

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克隆类型

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多克隆

标记

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This MEK1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
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    pSer217, pSer221

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

    免疫原

    Peptide sequence around phosphorylation site of serine 217/221 (I-D-S(p)-M-A) derived from Human MEK1/MEK2.

    亚型

    IgG
  • 应用备注

    WB:1:500-1:1000, IHC:1:50-1:100,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))

    别名

    MAP2K1

    背景

    Background: Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates ERK1 and ERK2 MAP kinases.Shen R, et al. (2002) Mol Cell Biol, 22(10): 3230-3236Preisinger C, et al. (2005) EMBO J, 24(4): 753-765Laine P, et al. (2000) Biochem J, 349(Pt 1): 19-25Yaglom J, et al. (2003) Mol Cell Biol, 23(11): 3813-3824Dahan S, et al. (2002) Infect Immun, 70(5): 2304-2310

    Aliases: Dual specificity mitogen activated protein kinase kinase 1 antibody, Dual specificity mitogen-activated protein kinase kinase 1 antibody, ERK activator kinase 1 antibody, MAP kinase kinase 1 antibody, MAP kinase/Erk kinase 1 antibody, MAP2K1 antibody, MAPK/ERK kinase 1 antibody, MAPKK 1 antibody, MAPKK1 antibody, MEK 1 antibody, Mek1 antibody, MEKK1 antibody, Mitogen activated protein kinase kinase 1 antibody, MKK 1 antibody, MKK1 antibody, MP2K1_HUMAN antibody, PRKMK1 antibody, Protein kinase mitogen activated kinase 1 (MAP kinase kinase 1) antibody, Protein kinase mitogen activated, kinase 1 antibody, protein kinase mitogen-activated kinase 1 antibody

    UniProt

    Q02750

    途径

    MAPK Pathway, RTK signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling
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