NR5A1 抗体 (AA 220-461)
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- 抗原 See all NR5A1 抗体
- NR5A1 (Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1))
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抗原表位
- AA 220-461
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This NR5A1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- The protein encoded by this gene is a transcriptional activator involved in sex determination. The encoded protein binds DNA as a monomer. Defects in this gene are a cause of XY sex reversal with or without adrenal failure as well as adrenocortical insufficiency without ovarian defect. Steroidogenic Factor 1 (SF-1) is considered an orphan nuclear receptor that belongs to subfamily 5. It was found to be a regulator of steroidogenic enzyme gene expression. Oxysterols are suggested as its ligands. It is expressed in all steroidogenic tissues, including the adrenal cortex, testicular Sertoli cells, and Leydig cells, ovarian theca, hypothalamus, and anterior pituitary. SF-1 plays an important role in adrenal and gonadal development. SF-1 is highly valuable marker to determine the adrenocortical origin of an adrenal mass.
- 交叉反应 （详细）
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant fragment (around aa220-461) of human SF-1 protein
- 亚型
- IgG2b
- Top Product
- Discover our top product NR5A1 Primary Antibody
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anti-Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1) (Middle Region) antibody
NR5A1 适用: 人, 小鼠, 大鼠, 豚鼠, 马, 兔, 犬, Cow, 绵羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1) (AA 172-221) antibodyNR5A1 适用: 人, 兔, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1) (Internal Region) antibodyNR5A1 适用: 人, 猴, Bat IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1) (AA 1-120) antibodyNR5A1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1) (AA 64-93), (N-Term) antibodyNR5A1 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB26159 unconjugated
anti-Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1) (Middle Region) antibodyNR5A1 适用: 人, 大鼠, 豚鼠, 马, 兔, 犬, Cow, 绵羊, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1) antibodyNR5A1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1) (AA 174-223) antibodyNR5A1 适用: 人, 小鼠, 大鼠, 豚鼠, 马, Cow, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1) (AA 358-407) antibodyNR5A1 适用: 小鼠, 大鼠, 豚鼠, 马, 兔, 犬, Pig, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1) (AA 169-218) antibodyNR5A1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human testis or adrenal cortical carcinoma.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- NR5A1 (Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1))
- 别名
- NR5A1 (NR5A1 产品)
- 别名
- AD4BP antibody, ELP antibody, FTZ1 antibody, FTZF1 antibody, POF7 antibody, SF-1 antibody, SF1 antibody, SPGF8 antibody, SRXY3 antibody, Ad4BP antibody, ELP-3 antibody, Ftz-F1 antibody, Ftzf1 antibody, Ad4BP/SF-1 antibody, Ad4bp antibody, Sf-1 antibody, NR5A1 antibody, sf-1 antibody, elp antibody, sf1 antibody, ftz1 antibody, ad4bp antibody, ftzf1 antibody, SF-1/Ad4BP antibody, SI:zC167P9.2 antibody, ff1d antibody, nr5a2l antibody, nuclear receptor subfamily 5 group A member 1 antibody, nuclear receptor subfamily 5, group A, member 1 antibody, nuclear receptor subfamily 5 group A member 1 L homeolog antibody, nuclear receptor subfamily 6 group A member 1 antibody, nuclear receptor subfamily 5, group A, member 1b antibody, NR5A1 antibody, Nr5a1 antibody, nr5a1.L antibody, nr5a1 antibody, NR6A1 antibody, nr5a1b antibody
- 背景
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Adrenal 4 binding protein (AD4BP), ELP, Fushi tarazu factor homolog 1 (FTZ1), Nuclear receptor AdBP4, Nuclear receptor subfamily 5 group A member 1 (NR5A1), POF7, SPGF8, SRXY3, Steroid hormone receptor Ad4BP, Steroidogenic factor 1 (SF1), Steroidogenic factor 1 nuclear receptor, STF1,Steroidogenic Factor 1 (SF-1) (Transcription Factor)
Cellular localisation: Nucleus. - 分子量
- 53kDa
- 基因ID
- 2516, 495108
- UniProt
- Q13285
- 途径
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Maintenance of Protein Location
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