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GPR177/WLS 抗体

WLS 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7120857
发货至: 中国
  • 抗原 See all GPR177/WLS (WLS) 抗体
    GPR177/WLS (WLS) (Wntless Homolog (WLS))
    适用
    • 19
    • 14
    • 13
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 18
    • 1
    克隆类型
    • 19
    多克隆
    标记
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GPR177/WLS antibody is un-conjugated
    应用范围
    • 7
    • 7
    • 6
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    G protein-coupled receptor 177
    亚型
    IgG
    Top Product
    Discover our top product WLS Primary Antibody
  • 应用备注
    WB: 1:500-1:1000, IP: 1:500-1:1000, IHC: 1:20-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    GPR177/WLS (WLS) (Wntless Homolog (WLS))
    别名
    GPR177 (WLS 产品)
    别名
    C1orf139 antibody, EVI antibody, GPR177 antibody, MRP antibody, mig-14 antibody, 5031439A09Rik antibody, AI173978 antibody, AI987742 antibody, Gpr177 antibody, gpr117 antibody, gpr177 antibody, sb:cb610 antibody, wu:fb36d04 antibody, wu:fb44d10 antibody, wu:fb50c06 antibody, zgc:64091 antibody, CG6210 antibody, Dmel\\CG6210 antibody, Evi antibody, Evi/Wls antibody, Srt antibody, Wls antibody, Wls/Evi antibody, evi antibody, srt antibody, wls/evi antibody, wntless Wnt ligand secretion mediator antibody, wntless homolog (Drosophila) antibody, wntless antibody, WLS antibody, Wls antibody, wls antibody
    背景
    Synonyms:C1orf139, EVI, G protein coupled receptor 177, GPR177, Protein wntless homolog, Sprinter, WLS, Wntless Background:GPR177, also known as Wntless (WLS) or Evi, is an evolutionarily conserved transmembrane protein necessary for Wnt protein secretion. GPR177 localizes to compartments of the secretory pathway, including the ER, Golgi apparatus, endosomes, and plasma membrane. GPR177 is overexpressed in several cancer types including glioma and gastric cancer. Several isoforms of GPR177 exist due to the alternative splicing, with predicted MW around 62 and 51 kDa, respectively. The sequence can be processed by removing the signal peptide, which generates a mature form of 45-46 kDa. In addition, slow migragrating band above 62 kDa can also be detected because GPR177 is modified by N-linked glycosylation (PMID: 20549736).
    分子量
    46-62 kDa
    基因ID
    79971
    UniProt
    Q5T9L3
    途径
    WNT signaling
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