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ULBP2 抗体

ULBP2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7120611
发货至: 中国
  • 抗原 See all ULBP2 抗体
    ULBP2 (UL16 Binding Protein 2 (ULBP2))
    适用
    • 23
    • 1
    • 1
    宿主
    • 18
    • 5
    克隆类型
    • 20
    • 3
    多克隆
    标记
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    This ULBP2 antibody is un-conjugated
    应用范围
    • 21
    • 15
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    UL16 binding protein 2
    亚型
    IgG
    Top Product
    Discover our top product ULBP2 Primary Antibody
  • 应用备注
    WB: 1:500-1:5000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    ULBP2 (UL16 Binding Protein 2 (ULBP2))
    别名
    ULBP2 (ULBP2 产品)
    别名
    N2DL2 antibody, RAET1H antibody, UL16 binding protein 2 antibody, NKG2D ligand 2-like antibody, ULBP2 antibody, LOC100355436 antibody
    背景
    Synonyms:ALCAN alpha, N2DL 2, N2DL2, NKG2D ligand 2, NKG2DL2, RAET1H, UL16 binding protein 2, ULBP2 Background:Ligand for the KLRK1/NKG2D receptor, together with at least ULBP1 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to KLRK1/NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked the interaction with the KLRK1/NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system. UL16 also causes ULBP2 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface.
    分子量
    30-35 kDa
    基因ID
    80328
    UniProt
    Q9BZM5
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