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ULBP2 抗体 (AA 26-216)

ULBP2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7161653
发货至: 中国
  • 抗原 See all ULBP2 抗体
    ULBP2 (UL16 Binding Protein 2 (ULBP2))
    抗原表位
    • 7
    • 6
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 26-216
    适用
    • 22
    • 1
    • 1
    宿主
    • 17
    • 5
    克隆类型
    • 19
    • 3
    多克隆
    标记
    • 12
    • 2
    • 2
    • 2
    • 2
    • 2
    This ULBP2 antibody is un-conjugated
    应用范围
    • 21
    • 14
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    Antigen Affinity Purified
    免疫原
    Recombinant Human NKG2D ligand 2 protein (26-216AA)
    亚型
    IgG
    Top Product
    Discover our top product ULBP2 Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    ULBP2 (UL16 Binding Protein 2 (ULBP2))
    别名
    ULBP2 (ULBP2 产品)
    别名
    N2DL2 antibody, RAET1H antibody, UL16 binding protein 2 antibody, NKG2D ligand 2-like antibody, ULBP2 antibody, LOC100355436 antibody
    背景

    Background: Ligand for the KLRK1/NKG2D receptor, together with at least ULBP1 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to KLRK1/NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked the interaction with the KLRK1/NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system. UL16 also causes ULBP2 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface.

    Aliases: ALCAN alpha antibody, ALCAN-alpha antibody, N2DL 2 antibody, N2DL-2 antibody, N2DL2 antibody, N2DL2_HUMAN antibody, NKG2D ligand 2 antibody, NKG2D ligand 2 precursor antibody, NKG2DL2 antibody, RAET1H antibody, Retinoic acid early transcript 1 H antibody, Retinoic acid early transcript 1H antibody, UL16 binding protein 2 antibody, UL16-binding protein 2 antibody, ULBP2 antibody

    UniProt
    Q9BZM5
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