TCF7L2 抗体
Quick Overview for TCF7L2 抗体 (ABIN7120060)
抗原
See all TCF7L2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- TCF7L2 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- transcription factor 7-like 2(T-cell specific, HMG-box)
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亚型
- IgG
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anti-Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2) antibody
TCF7L2 适用: 人, 小鼠, 大鼠 WB, IF (cc), IHC (p), IHC, FACS 宿主: 兔 Monoclonal 2C2 unconjugated
anti-Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2) (AA 490-596) antibodyTCF7L2 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 3A4 unconjugated
anti-Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2) (AA 1-455) antibodyTCF7L2 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 1B1 unconjugated
anti-Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2) (N-Term) antibodyTCF7L2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2) (AA 490-596) antibodyTCF7L2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1A1 unconjugated
anti-Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2) (AA 1-455) antibodyTCF7L2 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1A9 unconjugated
anti-Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2) (Middle Region) antibodyTCF7L2 适用: 人, 小鼠, 大鼠, Cow, 斑马鱼, 豚鼠, 马, 兔, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2) (AA 61-90), (N-Term) antibodyTCF7L2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB19650 unconjugated
anti-Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2) (AA 401-550) antibodyTCF7L2 适用: 大鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2) (AA 490-596) antibodyTCF7L2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IP: 1:200-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- TCF7L2 (Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2))
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别名
- TCF7L2
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背景
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Synonyms: Transcription factor 7-like 2|HMG box transcription factor 4|T-cell-specific transcription factor 4 (T-cell factor 4, TCF-4, hTCF-4)|TCF7L2|TCF4
Background: Participates in the Wnt signaling pathway and modulates MYC expression by binding to its promoter in a sequence-specific manner. Acts as repressor in the absence of CTNNB1, and as activator in its presence. Activates transcription from promoters with several copies of the Tcf motif 5'-CCTTTGATC-3' in the presence of CTNNB1. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7L2/TCF4 and CTNNB1. Expression of dominant-negative mutants results in cell-cycle arrest in G1. Necessary for the maintenance of the epithelial stem-cell compartment of the small intestine.
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分子量
- 68 kDa
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基因ID
- 6934
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UniProt
- Q9NQB0
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途径
- WNT signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Regulation of Hormone Metabolic Process, Carbohydrate Homeostasis, Stem Cell Maintenance, Protein targeting to Nucleus
抗原
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