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TCF7L2 抗体 (Middle Region)

TCF7L2 适用: 人, 大鼠, 小鼠, Cow, 斑马鱼, 豚鼠, 兔, 马, 犬 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2777927
发货至: 中国
  • 抗原 See all TCF7L2 抗体
    TCF7L2 (Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2))
    抗原表位
    • 15
    • 11
    • 11
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    人, 大鼠, 小鼠, Cow, 斑马鱼, 豚鼠, 兔, 马, 犬
    宿主
    • 61
    • 7
    克隆类型
    • 52
    • 16
    多克隆
    标记
    • 29
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TCF7L2 antibody is un-conjugated
    应用范围
    • 46
    • 25
    • 18
    • 14
    • 13
    • 9
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    GGFRHPYPTA LTVNASMSRF PPHMVPPHHT LHTTGIPHPA IVTPTVKQES
    预测反应
    Cow: 92%, Dog: 92%, Guinea Pig: 92%, Horse: 92%, Human: 92%, Mouse: 92%, Rabbit: 92%, Rat: 92%, Zebrafish: 92%
    产品特性
    This is a rabbit polyclonal antibody against TCF7L2. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human TCF7L2
    Top Product
    Discover our top product TCF7L2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 596 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    TCF7L2 (Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2))
    别名
    TCF7L2 (TCF7L2 产品)
    别名
    TCF4B antibody, TCF4E antibody, Tcf-4 antibody, Tcf4 antibody, mTcf-4B antibody, mTcf-4E antibody, tcf4 antibody, XTCF-4 antibody, tcf4e antibody, TCF4 antibody, TCF-4 antibody, TCFL2 antibody, transcription factor 7 like 2 antibody, transcription factor 7-like 2 antibody, transcription factor 7 like 2, T cell specific, HMG box antibody, transcription factor 7 like 2 L homeolog antibody, transcription factor 7-like 2 (T-cell specific, HMG-box) antibody, TCF7L2 antibody, LOC100545943 antibody, Tcf7l2 antibody, tcf7l2 antibody, tcf7l2.L antibody
    背景
    The TCL7L2 is a high mobility group (HMG) box-containing transcription factor implicated in blood glucose homeostasis. The study of Yi et al. suggested that TCL7L2 acts through regulation of proglucagon through repression of the proglucagon gene in enteroendocrine cells via the Wnt signaling pathway. The TCL7L2 gene product is a high mobility group (HMG) box-containing transcription factor implicated in blood glucose homeostasis. The study of Yi et al. (2005) [PubMed 15525634] suggested that TCL7L2 acts through regulation of proglucagon (MIM 138030) through repression of the proglucagon gene in enteroendocrine cells via the Wnt signaling pathway.[supplied by OMIM]. Sequence Note: This gene (TCF7L2, alias TCF-4) is distinct from TCF4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-202 DA473655.1 1-202 203-251 Y11306.2 3-51 252-1252 AK225809.1 256-1256 1253-1305 Y11306.2 1053-1105 1306-1756 AK225809.1 1310-1760 1757-1811 Y11306.2 1557-1611 1812-2652 AK225809.1 1765-2605
    Alias Symbols: TCF-4, TCF4
    Protein Interaction Partner: UBC, FBLN1, UBE2I, PSMA3, MAD2L2, ZBTB33, DAXX, CTNNB1, ELAVL1, PARP1, XRCC5, SUMO2, XRCC6, NR5A1, EP300, CEBPA, CTBP1, DAZAP2, CTNNBIP1, JUP, CSNK2A2, CSNK2A1, PSEN1, NLK, RAC1,
    Protein Size: 596
    分子量
    65 kDa
    基因ID
    6934
    NCBI登录号
    NM_030756, NP_110383
    UniProt
    Q6FHW4
    途径
    WNT signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Regulation of Hormone Metabolic Process, Carbohydrate Homeostasis, Stem Cell Maintenance, Protein targeting to Nucleus
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