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SET/TAF-I 抗体 (AA 160-290)

This anti-SET/TAF-I antibody is a 兔 多克隆 antibody detecting SET/TAF-I in WB, IHC 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7118995
发货至: 中国

Quick Overview for SET/TAF-I 抗体 (AA 160-290) (ABIN7118995)

抗原

See all SET/TAF-I (SET) 抗体
SET/TAF-I (SET) (SET Nuclear Oncogene (SET))

适用

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人, 小鼠, 大鼠

宿主

  • 67
  • 3
  • 2

克隆类型

  • 57
  • 14
多克隆

标记

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This SET/TAF-I antibody is un-conjugated

应用范围

  • 49
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  • 1
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 8
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    • 2
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    • 1
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    AA 160-290

    原理

    SET antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    Immunogen sequence: 160-290aa

    Immunogen: SET nuclear oncogene

    亚型

    IgG
  • 应用备注

    WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    SET/TAF-I (SET) (SET Nuclear Oncogene (SET))

    别名

    SET

    背景

    Synonyms: Protein SET|HLA-DR-associated protein II|Inhibitor of granzyme A-activated DNase (IGAAD)|PHAPII|Phosphatase 2A inhibitor I2PP2A (I-2PP2A)|Template-activating factor I (TAF-I)|SET

    Background: The protein encoded by this gene inhibits acetylation of nucleosomes, especially histone H4, by histone acetylases (HAT). This inhibition is most likely accomplished by masking histone lysines from being acetylated, and the consequence is to silence HAT-dependent transcription. The encoded protein is part of a complex localized to the endoplasmic reticulum but is found in the nucleus and inhibits apoptosis following attack by cytotoxic T lymphocytes. This protein can also enhance DNA replication of the adenovirus genome. Several transcript variants encoding different isoforms have been found for this gene.

    分子量

    33 kDa

    基因ID

    6418

    UniProt

    Q01105

    途径

    Apoptosis
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