SET/TAF-I 抗体 (AA 160-290)
Quick Overview for SET/TAF-I 抗体 (AA 160-290) (ABIN7118995)
抗原
See all SET/TAF-I (SET) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 160-290
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原理
- SET antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 160-290aa
Immunogen: SET nuclear oncogene
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亚型
- IgG
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应用备注
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- SET/TAF-I (SET) (SET Nuclear Oncogene (SET))
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别名
- SET
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背景
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Synonyms: Protein SET|HLA-DR-associated protein II|Inhibitor of granzyme A-activated DNase (IGAAD)|PHAPII|Phosphatase 2A inhibitor I2PP2A (I-2PP2A)|Template-activating factor I (TAF-I)|SET
Background: The protein encoded by this gene inhibits acetylation of nucleosomes, especially histone H4, by histone acetylases (HAT). This inhibition is most likely accomplished by masking histone lysines from being acetylated, and the consequence is to silence HAT-dependent transcription. The encoded protein is part of a complex localized to the endoplasmic reticulum but is found in the nucleus and inhibits apoptosis following attack by cytotoxic T lymphocytes. This protein can also enhance DNA replication of the adenovirus genome. Several transcript variants encoding different isoforms have been found for this gene.
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分子量
- 33 kDa
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基因ID
- 6418
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UniProt
- Q01105
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途径
- Apoptosis
抗原
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