电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

NEIL3 抗体

NEIL3 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7116771
发货至: 中国
  • 抗原 See all NEIL3 抗体
    NEIL3 (Nei Endonuclease VIII-Like 3 (NEIL3))
    适用
    • 20
    • 6
    • 2
    人, 小鼠
    宿主
    • 20
    • 1
    克隆类型
    • 20
    • 1
    多克隆
    标记
    • 11
    • 2
    • 2
    • 2
    • 2
    • 2
    This NEIL3 antibody is un-conjugated
    应用范围
    • 21
    • 16
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    nei endonuclease VIII-like 3(E. coli)
    亚型
    IgG
    Top Product
    Discover our top product NEIL3 Primary Antibody
  • 应用备注
    WB: 1:500-1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    NEIL3 (Nei Endonuclease VIII-Like 3 (NEIL3))
    别名
    NEIL3 (NEIL3 产品)
    别名
    RGD1310562 antibody, NEIL3 antibody, zgc:103553 antibody, neil3 antibody, MAC12.12 antibody, MAC12_12 antibody, FGP2 antibody, FPG2 antibody, NEI3 antibody, hFPG2 antibody, hNEI3 antibody, AI449477 antibody, BC034753 antibody, C85903 antibody, nei-like DNA glycosylase 3 antibody, nei like DNA glycosylase 3 antibody, GRF zinc finger / Zinc knuckle protein antibody, nei-like DNA glycosylase 3 L homeolog antibody, nei like 3 (E. coli) antibody, Neil3 antibody, NEIL3 antibody, neil3 antibody, AT5G13920 antibody, neil3.L antibody
    背景
    Synonyms: Background:DNA glycosylase which prefers single-stranded DNA(ssDNA), or partially ssDNA structures such as bubble and fork structures, to double-stranded DNA(dsDNA). In vitro, displays strong glycosylase activity towards the hydantoin lesions spiroiminodihydantoin(Sp) and guanidinohydantoin(Gh) in both ssDNA and dsDNA, also recognizes FapyA, FapyG, 5-OHU, 5-OHC, 5-OHMH, Tg and 8-oxoA lesions in ssDNA. No activity on 8-oxoG detected. Also shows weak DNA-(apurinic or apyrimidinic site) lyase activity. In vivo, appears to be the primary enzyme involved in removing Sp and Gh from ssDNA in neonatal tissues. Seems to be an important facilitator of cell proliferation in certain populations, for example neural stem/progenitor cells and tumor cells, suggesting a role in replication-associated DNA repair.
    分子量
    62-68 kDa
    基因ID
    55247
    UniProt
    Q8TAT5
    途径
    DNA Damage Repair
You are here: