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MSH3 抗体

MSH3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7116541
发货至: 中国
  • 抗原 See all MSH3 抗体
    MSH3 (MutS Homolog 3 (MSH3))
    适用
    • 29
    • 3
    • 2
    宿主
    • 29
    克隆类型
    • 28
    • 1
    多克隆
    标记
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    • 1
    • 1
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    This MSH3 antibody is un-conjugated
    应用范围
    • 13
    • 13
    • 13
    • 9
    • 7
    • 4
    • 4
    • 4
    • 4
    • 2
    Western Blotting (WB), ELISA
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    mutS homolog 3
    亚型
    IgG
    Top Product
    Discover our top product MSH3 Primary Antibody
  • 应用备注
    WB: 1:500-1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    MSH3 (MutS Homolog 3 (MSH3))
    别名
    MSH3 (MSH3 产品)
    别名
    ATMSH3 antibody, M7J2.90 antibody, M7J2_90 antibody, homolog of DNA mismatch repair protein MSH3 antibody, DUP antibody, MRP1 antibody, D13Em1 antibody, Rep-3 antibody, Rep3 antibody, mutS homolog 3 antibody, DNA mismatch repair protein MSH3 antibody, homolog of DNA mismatch repair protein MSH3 antibody, mismatch repair protein antibody, MSH3 antibody, Msh3 antibody
    背景
    Synonyms:DUC1, DUG Background:Component of the post-replicative DNA mismatch repair system(MMR). Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion-deletion loops(IDL) up to 13 nucleotides long. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.
    分子量
    123 kDa
    基因ID
    4437
    UniProt
    P20585
    途径
    DNA Damage Repair, Production of Molecular Mediator of Immune Response
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