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Insulin 抗体 (AA 1-110)

The 小鼠 单克隆 anti-Insulin antibody is suitable to detect Insulin in samples from 人 和 小鼠. It has been validated for IHC 和 ELISA.
产品编号 ABIN7115273
发货至: 中国
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Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Insulin 抗体 (AA 1-110) (ABIN7115273)

抗原

See all Insulin (INS) 抗体
Insulin (INS)

适用

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人, 小鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This Insulin antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA

克隆位点

0H2
  • 抗原表位

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    AA 1-110

    原理

    INS antibody

    纯化方法

    Protein A+G purification

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    Immunogen sequence: 1-110aa

    Immunogen: insulin

    亚型

    IgG2a
  • 应用备注

    IHC: 1:500-1:5000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    Insulin (INS)

    别名

    INS

    背景

    Synonyms: Insulin|Insulin B chain|Insulin A chain|INS

    Background: Insulin is a peptide hormone, produced by beta cells of the pancreas, and is central to regulating carbohydrate and fat metabolism in the body. It participates in glucose utilization, protein synthesis and in the formation and storage of neutral lipids. Insulin is synthesized as a precursor molecule, proinsulin, which is processed prior to secretion. A-and B-peptides are joined together by a disulfide bond to form insulin, while the central portion of the precursor molecule is cleaved and released as the C-peptide. Defects in insulin results in type 1 diabetes mellitus. Insulin may also exist 36 kDa form corresponding to the hexameric insulin form.

    基因ID

    3630

    UniProt

    P01308

    途径

    NF-kappaB Signaling, RTK signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
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