GRB2 抗体
Quick Overview for GRB2 抗体 (ABIN7114784)
抗原
See all GRB2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- GRB2 antibody
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- growth factor receptor-bound protein 2
-
亚型
- IgG
-
-
-
-
应用备注
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:10 - 1:100
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months
-
有效期
- 12 months
-
-
- GRB2 (Growth Factor Receptor-Bound Protein 2 (GRB2))
-
别名
- GRB2
-
背景
-
Synonyms: Growth factor receptor-bound protein 2|Adapter protein GRB2|Protein Ash|SH2/SH3 adapter GRB2|GRB2|ASH
Background: The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
-
分子量
- 33 kDa
-
基因ID
- 2885
-
UniProt
- P62993
-
途径
- RTK signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, Hepatitis C, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, EGFR Downregulation
抗原
-