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RAD51 抗体

This anti-RAD51 antibody is a 兔 多克隆 antibody detecting RAD51 in WB, ELISA, IHC 和 IP. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7113555
发货至: 中国

Quick Overview for RAD51 抗体 (ABIN7113555)

抗原

See all RAD51 抗体
RAD51 (DNA Repair Protein Homolog 1 (RAD51))

适用

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人, 小鼠, 大鼠

宿主

  • 106
  • 62
  • 1

克隆类型

  • 97
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多克隆

标记

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This RAD51 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    RAD51 homolog

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:5000, IP: 1:500-1:5000, IHC: 1:50-1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    RAD51 (DNA Repair Protein Homolog 1 (RAD51))

    别名

    RAD51

    背景

    Synonyms:RAD51A, RECA Background:Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange(PubMed:26681308). Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3.

    分子量

    37 kDa

    基因ID

    5888

    UniProt

    Q06609

    途径

    DNA Damage Repair
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