CDC42 抗体
Quick Overview for CDC42 抗体 (ABIN7112573)
抗原
See all CDC42 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- CDC42 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- cell division cycle 42 (GTP binding protein, 25kDa)
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亚型
- IgG
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anti-Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) (AA 25-191) antibody
CDC42 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) antibodyCDC42 适用: 人 WB, ELISA, IHC 宿主: 兔 Monoclonal 3C3 unconjugated Recombinant Antibody
anti-Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) (AA 1-191) antibodyCDC42 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) (AA 121-138), (Middle Region) antibodyCDC42 适用: 人, 小鼠, 大鼠, Cow WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) antibodyCDC42 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) (AA 1-188) antibodyCDC42 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) (AA 2-188) antibodyCDC42 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) antibodyCDC42 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) (AA 38-87) antibodyCDC42 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 猴, 小鸡, 兔, 马, 非洲爪蟾, Insect, 豚鼠, Avian WB 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) antibodyCDC42 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal unconjugated
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应用备注
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- CDC42 (Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42))
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别名
- CDC42
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背景
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Synonyms: Cell division control protein 42 homolog|G25K GTP-binding protein|CDC42
Background: The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20.
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分子量
- 21 kDa
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基因ID
- 998
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UniProt
- P60953
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途径
- MAPK Pathway, Microtubule Dynamics, RTK signaling, WNT signaling, TCR Signaling, EGFR Signaling Pathway, Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Signaling Events mediated by VEGFR1 and VEGFR2, EGFR Downregulation, VEGF Signaling
抗原
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