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CTCFL 抗体

CTCFL 适用: 人, 小鼠 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2B10 unconjugated
产品编号 ABIN7112427
发货至: 中国
  • 抗原 See all CTCFL 抗体
    CTCFL (CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL))
    适用
    • 27
    • 10
    • 3
    人, 小鼠
    宿主
    • 31
    • 1
    • 1
    小鼠
    克隆类型
    • 32
    • 1
    单克隆
    标记
    • 15
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CTCFL antibody is un-conjugated
    应用范围
    • 27
    • 13
    • 13
    • 11
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    纯化方法
    Protein A+G purification
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    CCCTC-binding factor(zinc finger protein)-like
    克隆位点
    2B10
    亚型
    IgG1
    Top Product
    Discover our top product CTCFL Primary Antibody
  • 应用备注
    WB: 1:500-1:2000, IF: 1:10-1:100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    CTCFL (CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL))
    别名
    BORIS (CTCFL 产品)
    别名
    BORIS antibody, CT27 antibody, CTCF-T antibody, HMGB1L1 antibody, dJ579F20.2 antibody, CTCFL antibody, Boris antibody, OTTMUSG00000016680 antibody, CCCTC-binding factor like antibody, CCCTC-binding factor (zinc finger protein)-like antibody, CTCFL antibody, Ctcfl antibody
    背景
    Synonyms:BORIS, Cancer/testis antigen 27, CCCTC binding factor, CT27, CTCF like protein, CTCF paralog, CTCF T, CTCFL, dJ579F20.2, Zinc finger protein CTCF T Background:CTCFL, also named BORIS(for brother of the regulator of imprinted sites) is a paralogue of the 11 zinc-finger transcription factor, CTCF. It is predominantly expressed in spermatocytes in the testis, also can be found in tumors and cancer cell lines. It mainly participates in insulator function, nuclear architecture and transcriptional control, which probably acts by recruiting epigenetic chromatin modifiers. It has a key role in gene imprinting in male germline, by participating in the establishment of differential methylation at the IGF2/H19 imprinted control region(ICR). Directly binds the unmethylated H19 ICR and recruits the PRMT7 methyltransferase, leading to methylate histone H4 'Arg-3' to form H4R3sme2.
    分子量
    75 kDa
    UniProt
    Q8NI51
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